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Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture.
Laurent LC, Ulitsky I, Slavin I, Tran H, Schork A, Morey R, Lynch C, Harness JV, Lee S, Barrero MJ, Ku S, Martynova M, Semechkin R, Galat V, Gottesfeld J, Izpisua Belmonte JC, Murry C, Keirstead HS, Park HS, Schmidt U, Laslett AL, Muller FJ, Nievergelt CM, Shamir R, Loring JF. Laurent LC, et al. Cell Stem Cell. 2011 Jan 7;8(1):106-18. doi: 10.1016/j.stem.2010.12.003. Cell Stem Cell. 2011. PMID: 21211785 Free PMC article.
The epigenome in pluripotency and differentiation.
Thiagarajan RD, Morey R, Laurent LC. Thiagarajan RD, et al. Among authors: laurent lc. Epigenomics. 2014 Feb;6(1):121-37. doi: 10.2217/epi.13.80. Epigenomics. 2014. PMID: 24579950 Review.
Abnormalities in human pluripotent cells due to reprogramming mechanisms.
Ma H, Morey R, O'Neil RC, He Y, Daughtry B, Schultz MD, Hariharan M, Nery JR, Castanon R, Sabatini K, Thiagarajan RD, Tachibana M, Kang E, Tippner-Hedges R, Ahmed R, Gutierrez NM, Van Dyken C, Polat A, Sugawara A, Sparman M, Gokhale S, Amato P, Wolf DP, Ecker JR, Laurent LC, Mitalipov S. Ma H, et al. Among authors: laurent lc. Nature. 2014 Jul 10;511(7508):177-83. doi: 10.1038/nature13551. Epub 2014 Jul 2. Nature. 2014. PMID: 25008523 Free PMC article.
Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions.
Garitaonandia I, Amir H, Boscolo FS, Wambua GK, Schultheisz HL, Sabatini K, Morey R, Waltz S, Wang YC, Tran H, Leonardo TR, Nazor K, Slavin I, Lynch C, Li Y, Coleman R, Gallego Romero I, Altun G, Reynolds D, Dalton S, Parast M, Loring JF, Laurent LC. Garitaonandia I, et al. Among authors: laurent lc. PLoS One. 2015 Feb 25;10(2):e0118307. doi: 10.1371/journal.pone.0118307. eCollection 2015. PLoS One. 2015. PMID: 25714340 Free PMC article.
Proof of concept studies exploring the safety and functional activity of human parthenogenetic-derived neural stem cells for the treatment of Parkinson's disease.
Gonzalez R, Garitaonandia I, Crain A, Poustovoitov M, Abramihina T, Noskov A, Jiang C, Morey R, Laurent LC, Elsworth JD, Snyder EY, Redmond DE Jr, Semechkin R. Gonzalez R, et al. Among authors: laurent lc. Cell Transplant. 2015;24(4):681-90. doi: 10.3727/096368915X687769. Epub 2015 Mar 24. Cell Transplant. 2015. PMID: 25839189 Free article.
Metabolic rescue in pluripotent cells from patients with mtDNA disease.
Ma H, Folmes CD, Wu J, Morey R, Mora-Castilla S, Ocampo A, Ma L, Poulton J, Wang X, Ahmed R, Kang E, Lee Y, Hayama T, Li Y, Van Dyken C, Gutierrez NM, Tippner-Hedges R, Koski A, Mitalipov N, Amato P, Wolf DP, Huang T, Terzic A, Laurent LC, Izpisua Belmonte JC, Mitalipov S. Ma H, et al. Among authors: laurent lc. Nature. 2015 Aug 13;524(7564):234-8. doi: 10.1038/nature14546. Epub 2015 Jul 15. Nature. 2015. PMID: 26176921
164 results