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Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer.
Freire Boullosa L, Van Loenhout J, Flieswasser T, De Waele J, Hermans C, Lambrechts H, Cuypers B, Laukens K, Bartholomeus E, Siozopoulou V, De Vos WH, Peeters M, Smits ELJ, Deben C. Freire Boullosa L, et al. Among authors: laukens k. Redox Biol. 2021 Jun;42:101949. doi: 10.1016/j.redox.2021.101949. Epub 2021 Mar 19. Redox Biol. 2021. PMID: 33812801 Free PMC article.
The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein.
Wouters A, Pauwels B, Burrows N, Baay M, Deschoolmeester V, Vu TN, Laukens K, Meijnders P, Van Gestel D, Williams KJ, Van den Weyngaert D, Vermorken JB, Pauwels P, Peeters M, Lardon F. Wouters A, et al. Among authors: laukens k. BMC Cancer. 2014 Aug 16;14:594. doi: 10.1186/1471-2407-14-594. BMC Cancer. 2014. PMID: 25128202 Free PMC article.
Increased herpes zoster risk associated with poor HLA-A immediate early 62 protein (IE62) affinity.
Meysman P, De Neuter N, Bartholomeus E, Elias G, Van den Bergh J, Emonds MP, Haasnoot GW, Heynderickx S, Wens J, Michels NR, Lambert J, Lion E, Claas FHJ, Goossens H, Smits E, Van Damme P, Van Tendeloo V, Beutels P, Suls A, Mortier G, Laukens K, Ogunjimi B. Meysman P, et al. Among authors: laukens k. Immunogenetics. 2018 Jun;70(6):363-372. doi: 10.1007/s00251-017-1047-x. Epub 2017 Dec 1. Immunogenetics. 2018. PMID: 29196796
Transcriptome profiling in blood before and after hepatitis B vaccination shows significant differences in gene expression between responders and non-responders.
Bartholomeus E, De Neuter N, Meysman P, Suls A, Keersmaekers N, Elias G, Jansens H, Hens N, Smits E, Van Tendeloo V, Beutels P, Van Damme P, Ogunjimi B, Laukens K, Mortier G. Bartholomeus E, et al. Among authors: laukens k. Vaccine. 2018 Oct 8;36(42):6282-6289. doi: 10.1016/j.vaccine.2018.09.001. Epub 2018 Sep 8. Vaccine. 2018. PMID: 30205979 Clinical Trial.
169 results