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Page 1
Chromosomal instability drives metastasis through a cytosolic DNA response.
Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, Birkbak NJ, McGranahan N, Lundquist M, LaPlant Q, Healey JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe'er D, Cleveland DW, Powell SN, Lammerding J, Swanton C, Cantley LC. Bakhoum SF, et al. Among authors: laughney am. Nature. 2018 Jan 25;553(7689):467-472. doi: 10.1038/nature25432. Epub 2018 Jan 17. Nature. 2018. PMID: 29342134 Free PMC article.
Numerical chromosomal instability mediates susceptibility to radiation treatment.
Bakhoum SF, Kabeche L, Wood MD, Laucius CD, Qu D, Laughney AM, Reynolds GE, Louie RJ, Phillips J, Chan DA, Zaki BI, Murnane JP, Petritsch C, Compton DA. Bakhoum SF, et al. Among authors: laughney am. Nat Commun. 2015 Jan 21;6:5990. doi: 10.1038/ncomms6990. Nat Commun. 2015. PMID: 25606712 Free PMC article.
Adult Human Glioblastomas Harbor Radial Glia-like Cells.
Wang R, Sharma R, Shen X, Laughney AM, Funato K, Clark PJ, Shpokayte M, Morgenstern P, Navare M, Xu Y, Harbi S, Masilionis I, Nanjangud G, Yang Y, Duran-Rehbein G, Hemberg M, Pe'er D, Tabar V. Wang R, et al. Among authors: laughney am. Stem Cell Reports. 2020 Feb 11;14(2):338-350. doi: 10.1016/j.stemcr.2020.01.007. Epub 2020 Jan 30. Stem Cell Reports. 2020. PMID: 32004492 Free PMC article.
Regenerative lineages and immune-mediated pruning in lung cancer metastasis.
Laughney AM, Hu J, Campbell NR, Bakhoum SF, Setty M, Lavallée VP, Xie Y, Masilionis I, Carr AJ, Kottapalli S, Allaj V, Mattar M, Rekhtman N, Xavier JB, Mazutis L, Poirier JT, Rudin CM, Pe'er D, Massagué J. Laughney AM, et al. Nat Med. 2020 Feb;26(2):259-269. doi: 10.1038/s41591-019-0750-6. Epub 2020 Feb 10. Nat Med. 2020. PMID: 32042191 Free PMC article.
L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer.
Ganesh K, Basnet H, Kaygusuz Y, Laughney AM, He L, Sharma R, O'Rourke KP, Reuter VP, Huang YH, Turkekul M, Er EE, Masilionis I, Manova-Todorova K, Weiser MR, Saltz LB, Garcia-Aguilar J, Koche R, Lowe SW, Pe'er D, Shia J, Massagué J. Ganesh K, et al. Among authors: laughney am. Nat Cancer. 2020 Jan;1(1):28-45. doi: 10.1038/s43018-019-0006-x. Epub 2020 Jan 13. Nat Cancer. 2020. PMID: 32656539 Free PMC article.
Author Correction: L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer.
Ganesh K, Basnet H, Kaygusuz Y, Laughney AM, He L, Sharma R, O'Rourke KP, Reuter VP, Huang YH, Turkekul M, Er EE, Masilionis I, Manova-Todorova K, Weiser MR, Saltz LB, Garcia-Aguilar J, Koche R, Lowe SW, Pe'er D, Shia J, Massagué J. Ganesh K, et al. Among authors: laughney am. Nat Cancer. 2020 Nov;1(11):1128. doi: 10.1038/s43018-020-00130-3. Nat Cancer. 2020. PMID: 35122071 No abstract available.
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.
Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. Li Z, et al. Among authors: laughney am. Nat Commun. 2022 Oct 20;13(1):6239. doi: 10.1038/s41467-022-33862-0. Nat Commun. 2022. PMID: 36266345 Free PMC article.
32 results