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Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis.
Gaul S, Leszczynska A, Alegre F, Kaufmann B, Johnson CD, Adams LA, Wree A, Damm G, Seehofer D, Calvente CJ, Povero D, Kisseleva T, Eguchi A, McGeough MD, Hoffman HM, Pelegrin P, Laufs U, Feldstein AE. Gaul S, et al. Among authors: laufs u. J Hepatol. 2021 Jan;74(1):156-167. doi: 10.1016/j.jhep.2020.07.041. Epub 2020 Aug 4. J Hepatol. 2021. PMID: 32763266 Free PMC article.
Novel Nongenetic Murine Model of Hyperglycemia and Hyperlipidemia-Associated Aggravated Atherosclerosis.
Gaul S, Shahzad K, Medert R, Gadi I, Mäder C, Schumacher D, Wirth A, Ambreen S, Fatima S, Boeckel JN, Khawaja H, Haas J, Brune M, Nawroth PP, Isermann B, Laufs U, Freichel M. Gaul S, et al. Among authors: laufs u. Front Cardiovasc Med. 2022 Mar 8;9:813215. doi: 10.3389/fcvm.2022.813215. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35350534 Free PMC article.
Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.
Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, Klug M, Schunk SJ, Schmit D, Kramann R, Körbel C, Ampofo E, Laschke MW, Selejan SR, Paschen A, Herter T, Schuster S, Silbernagel G, Sester M, Sester U, Aßmann G, Bals R, Kostner G, Jahnen-Dechent W, Menger MD, Rohrer L, März W, Böhm M, Jankowski J, Kopf M, Latz E, Niemeyer BA, Fliser D, Laufs U, Speer T. Zewinger S, et al. Among authors: laufs u. Nat Immunol. 2020 Jan;21(1):30-41. doi: 10.1038/s41590-019-0548-1. Epub 2019 Dec 9. Nat Immunol. 2020. PMID: 31819254
Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality.
Schunk SJ, Kleber ME, März W, Pang S, Zewinger S, Triem S, Ege P, Reichert MC, Krawczyk M, Weber SN, Jaumann I, Schmit D, Sarakpi T, Wagenpfeil S, Kramann R, Boerwinkle E, Ballantyne CM, Grove ML, Tragante V, Pilbrow AP, Richards AM, Cameron VA, Doughty RN, Dubé MP, Tardif JC, Feroz-Zada Y, Sun M, Liu C, Ko YA, Quyyumi AA, Hartiala JA, Tang WHW, Hazen SL, Allayee H, McDonough CW, Gong Y, Cooper-DeHoff RM, Johnson JA, Scholz M, Teren A, Burkhardt R, Martinsson A, Smith JG, Wallentin L, James SK, Eriksson N, White H, Held C, Waterworth D, Trompet S, Jukema JW, Ford I, Stott DJ, Sattar N, Cresci S, Spertus JA, Campbell H, Tierling S, Walter J, Ampofo E, Niemeyer BA, Lipp P, Schunkert H, Böhm M, Koenig W, Fliser D, Laufs U, Speer T; eQTLGen consortium; BIOS consortium. Schunk SJ, et al. Among authors: laufs u. Eur Heart J. 2021 May 7;42(18):1742-1756. doi: 10.1093/eurheartj/ehab107. Eur Heart J. 2021. PMID: 33748830 Free PMC article.
SLM2 Is A Novel Cardiac Splicing Factor Involved in Heart Failure due to Dilated Cardiomyopathy.
Boeckel JN, Möbius-Winkler M, Müller M, Rebs S, Eger N, Schoppe L, Tappu R, Kokot KE, Kneuer JM, Gaul S, Bordalo DM, Lai A, Haas J, Ghanbari M, Drewe-Boss P, Liss M, Katus HA, Ohler U, Gotthardt M, Laufs U, Streckfuss-Bömeke K, Meder B. Boeckel JN, et al. Among authors: laufs u. Genomics Proteomics Bioinformatics. 2022 Feb;20(1):129-146. doi: 10.1016/j.gpb.2021.01.006. Epub 2021 Jul 15. Genomics Proteomics Bioinformatics. 2022. PMID: 34273561 Free PMC article.
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs.
Kokot KE, Kneuer JM, John D, Rebs S, Möbius-Winkler MN, Erbe S, Müller M, Andritschke M, Gaul S, Sheikh BN, Haas J, Thiele H, Müller OJ, Hille S, Leuschner F, Dimmeler S, Streckfuss-Bömeke K, Meder B, Laufs U, Boeckel JN. Kokot KE, et al. Among authors: laufs u. Basic Res Cardiol. 2022 Jun 23;117(1):32. doi: 10.1007/s00395-022-00940-9. Basic Res Cardiol. 2022. PMID: 35737129 Free PMC article.
Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form.
Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, Klug M, Schunk SJ, Schmit D, Kramann R, Körbel C, Ampofo E, Laschke MW, Selejan SR, Paschen A, Herter T, Gaul S, Silbernagel G, Sester M, Sester U, Aßmann G, Bals R, Kostner G, Jahnen-Dechent W, Menger MD, Rohrer L, März W, Böhm M, Jankowski J, Kopf M, Latz E, Niemeyer BA, Fliser D, Laufs U, Speer T. Zewinger S, et al. Among authors: laufs u. Nat Immunol. 2023 Mar;24(3):412-413. doi: 10.1038/s41590-023-01424-1. Epub 2023 Feb 13. Nat Immunol. 2023. PMID: 36781986 No abstract available.
Pathological phenotypes of LDL particles.
Laufs U, Weingärtner O. Laufs U, et al. Eur Heart J. 2018 Jul 14;39(27):2574-2576. doi: 10.1093/eurheartj/ehy387. Eur Heart J. 2018. PMID: 29982362 No abstract available.
571 results