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Synthesis and evaluation of novel 8,6-fused bicyclic peptidomimetic compounds as interleukin-1beta converting enzyme inhibitors.
O'Neil SV, Wang Y, Laufersweiler MC, Oppong KA, Soper DL, Wos JA, Ellis CD, Baize MW, Bosch GK, Fancher AN, Lu W, Suchanek MK, Wang RL, De B, Demuth TP Jr. O'Neil SV, et al. Among authors: laufersweiler mc. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5434-8. doi: 10.1016/j.bmcl.2005.08.109. Epub 2005 Oct 10. Bioorg Med Chem Lett. 2005. PMID: 16216507
Synthesis and evaluation of novel 1-(2-acylhydrazinocarbonyl)-cycloalkyl carboxamides as interleukin-1beta converting enzyme (ICE) inhibitors.
Soper DL, Sheville J, O'Neil SV, Wang Y, Laufersweiler MC, Oppong KA, Wos JA, Ellis CD, Fancher AN, Lu W, Suchanek MK, Wang RL, De B, Demuth TP Jr. Soper DL, et al. Among authors: laufersweiler mc. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4233-6. doi: 10.1016/j.bmcl.2006.05.076. Epub 2006 Jun 16. Bioorg Med Chem Lett. 2006. PMID: 16782334
Synthesis and evaluation of novel 8,5-fused bicyclic peptidomimetic compounds as interleukin-1beta converting enzyme (ICE) inhibitors.
Soper DL, Sheville JX, O'Neil SV, Wang Y, Laufersweiler MC, Oppong KA, Wos JA, Ellis CD, Baize MW, Chen JJ, Fancher AN, Lu W, Suchanek MK, Wang RL, Schwecke WP, Cruze CA, Buchalova M, Belkin M, Wireko F, Ritter A, De B, Wang D, Demuth TP Jr. Soper DL, et al. Among authors: laufersweiler mc. Bioorg Med Chem. 2006 Dec 1;14(23):7880-92. doi: 10.1016/j.bmc.2006.07.056. Bioorg Med Chem. 2006. PMID: 16908171
Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosis.
Hopkins CR, O'neil SV, Laufersweiler MC, Wang Y, Pokross M, Mekel M, Evdokimov A, Walter R, Kontoyianni M, Petrey ME, Sabatakos G, Roesgen JT, Richardson E, Demuth TP Jr. Hopkins CR, et al. Among authors: laufersweiler mc. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5659-63. doi: 10.1016/j.bmcl.2006.08.003. Epub 2006 Aug 21. Bioorg Med Chem Lett. 2006. PMID: 16919947
Synthesis and evaluation of unsaturated caprolactams as interleukin-1beta converting enzyme (ICE) inhibitors.
Wang Y, O'Neil SV, Wos JA, Oppong KA, Laufersweiler MC, Soper DL, Ellis CD, Baize MW, Fancher AN, Lu W, Suchanek MK, Wang RL, Schwecke WP, Cruze CA, Buchalova M, Belkin M, De B, Demuth TP Jr. Wang Y, et al. Among authors: laufersweiler mc. Bioorg Med Chem. 2007 Feb 1;15(3):1311-22. doi: 10.1016/j.bmc.2006.11.011. Epub 2006 Nov 10. Bioorg Med Chem. 2007. PMID: 17127070
Potent and selective carboxylic acid-based inhibitors of matrix metalloproteinases.
Pikul S, Ohler NE, Ciszewski G, Laufersweiler MC, Almstead NG, De B, Natchus MG, Hsieh LC, Janusz MJ, Peng SX, Branch TM, King SL, Taiwo YO, Mieling GE. Pikul S, et al. Among authors: laufersweiler mc. J Med Chem. 2001 Aug 2;44(16):2499-502. doi: 10.1021/jm015531s. J Med Chem. 2001. PMID: 11472202 No abstract available.
15 results