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PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3.
Salameh A, Lee AK, Cardó-Vila M, Nunes DN, Efstathiou E, Staquicini FI, Dobroff AS, Marchiò S, Navone NM, Hosoya H, Lauer RC, Wen S, Salmeron CC, Hoang A, Newsham I, Lima LA, Carraro DM, Oliviero S, Kolonin MG, Sidman RL, Do KA, Troncoso P, Logothetis CJ, Brentani RR, Calin GA, Cavenee WK, Dias-Neto E, Pasqualini R, Arap W. Salameh A, et al. Among authors: lauer rc. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8403-8. doi: 10.1073/pnas.1507882112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080435 Free PMC article.
Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer.
Ferrara F, Staquicini DI, Driessen WHP, D'Angelo S, Dobroff AS, Barry M, Lomo LC, Staquicini FI, Cardó-Vila M, Soghomonyan S, Alauddin MM, Flores LG 2nd, Arap MA, Lauer RC, Mathew P, Efstathiou E, Aparicio AM, Troncoso P, Navone NM, Logothetis CJ, Marchiò S, Gelovani JG, Sidman RL, Pasqualini R, Arap W. Ferrara F, et al. Among authors: lauer rc. Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12786-12791. doi: 10.1073/pnas.1615400113. Epub 2016 Oct 24. Proc Natl Acad Sci U S A. 2016. PMID: 27791181 Free PMC article.
Drug design strategies for the treatment of prostate cancer.
Lauer RC, Friend SC, Rietz C, Pasqualini R, Arap W. Lauer RC, et al. Expert Opin Drug Discov. 2015 Jan;10(1):81-90. doi: 10.1517/17460441.2015.978855. Epub 2014 Nov 4. Expert Opin Drug Discov. 2015. PMID: 25366417 Review.
A Phase I/II Trial of BNC105P with Everolimus in Metastatic Renal Cell Carcinoma.
Pal S, Azad A, Bhatia S, Drabkin H, Costello B, Sarantopoulos J, Kanesvaran R, Lauer R, Starodub A, Hauke R, Sweeney CJ, Hahn NM, Sonpavde G, Richey S, Breen T, Kremmidiotis G, Leske A, Doolin E, Bibby DC, Simpson J, Iglesias J, Hutson T. Pal S, et al. Clin Cancer Res. 2015 Aug 1;21(15):3420-7. doi: 10.1158/1078-0432.CCR-14-3370. Epub 2015 Mar 18. Clin Cancer Res. 2015. PMID: 25788492 Free PMC article. Clinical Trial.
Apatorsen plus docetaxel versus docetaxel alone in platinum-resistant metastatic urothelial carcinoma (Borealis-2).
Rosenberg JE, Hahn NM, Regan MM, Werner L, Alva A, George S, Picus J, Alter R, Balar A, Hoffman-Censits J, Grivas P, Lauer R, Guancial EA, Hoimes C, Sonpavde G, Albany C, Stein MN, Breen T, Jacobs C, Anderson K, Bellmunt J, Lalani AA, Pal S, Choueiri TK. Rosenberg JE, et al. Br J Cancer. 2018 May;118(11):1434-1441. doi: 10.1038/s41416-018-0087-9. Epub 2018 May 16. Br J Cancer. 2018. PMID: 29765151 Free PMC article. Clinical Trial.
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