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Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion.
Whiteside SK, Grant FM, Alvisi G, Clarke J, Tang L, Imianowski CJ, Zhang B, Evans AC, Wesolowski AJ, Conti AG, Yang J, Lauder SN, Clement M, Humphreys IR, Dooley J, Burton O, Liston A, Alloisio M, Voulaz E, Langhorne J, Okkenhaug K, Lugli E, Roychoudhuri R. Whiteside SK, et al. Among authors: lauder sn. Sci Immunol. 2023 Dec 15;8(90):eabo5558. doi: 10.1126/sciimmunol.abo5558. Epub 2023 Dec 15. Sci Immunol. 2023. PMID: 38100544 Free PMC article.
Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.
Clement M, Ladell K, Ekeruche-Makinde J, Miles JJ, Edwards ES, Dolton G, Williams T, Schauenburg AJ, Cole DK, Lauder SN, Gallimore AM, Godkin AJ, Burrows SR, Price DA, Sewell AK, Wooldridge L. Clement M, et al. Among authors: lauder sn. J Immunol. 2011 Jul 15;187(2):654-63. doi: 10.4049/jimmunol.1003941. Epub 2011 Jun 15. J Immunol. 2011. PMID: 21677135 Free PMC article.
T-cell trafficking facilitated by high endothelial venules is required for tumor control after regulatory T-cell depletion.
Hindley JP, Jones E, Smart K, Bridgeman H, Lauder SN, Ondondo B, Cutting S, Ladell K, Wynn KK, Withers D, Price DA, Ager A, Godkin AJ, Gallimore AM. Hindley JP, et al. Among authors: lauder sn. Cancer Res. 2012 Nov 1;72(21):5473-82. doi: 10.1158/0008-5472.CAN-12-1912. Epub 2012 Sep 7. Cancer Res. 2012. PMID: 22962270 Free PMC article.
PI3K Isoform Immunotherapy for Solid Tumours.
Scott J, Rees L, Gallimore A, Lauder SN. Scott J, et al. Among authors: lauder sn. Curr Top Microbiol Immunol. 2022;436:369-392. doi: 10.1007/978-3-031-06566-8_16. Curr Top Microbiol Immunol. 2022. PMID: 36243853 Review.
Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors.
Hindley JP, Ferreira C, Jones E, Lauder SN, Ladell K, Wynn KK, Betts GJ, Singh Y, Price DA, Godkin AJ, Dyson J, Gallimore A. Hindley JP, et al. Among authors: lauder sn. Cancer Res. 2011 Feb 1;71(3):736-46. doi: 10.1158/0008-5472.CAN-10-1797. Epub 2010 Dec 13. Cancer Res. 2011. PMID: 21156649 Free PMC article.
35 results