Lau KS - Search Results

1

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.

Chen B, Scurrah CR, McKinley ET, Simmons AJ, Ramirez-Solano MA, Zhu X, Markham NO, Heiser CN, Vega PN, Rolong A, Kim H, Sheng Q, Drewes JL, Zhou Y, Southard-Smith AN, Xu Y, Ro J, Jones AL, Revetta F, Berry LD, Niitsu H, Islam M, Pelka K, Hofree M, Chen JH, Sarkizova S, Ng K, Giannakis M, Boland GM, Aguirre AJ, Anderson AC, Rozenblatt-Rosen O, Regev A, Hacohen N, Kawasaki K, Sato T, Goettel JA, Grady WM, Zheng W, Washington MK, Cai Q, Sears CL, Goldenring JR, Franklin JL, Su T, Huh WJ, Vandekar S, Roland JT, Liu Q, Coffey RJ, Shrubsole MJ, Lau KS. Chen B, et al. Among authors: lau ks. Cell. 2021 Dec 22;184(26):6262-6280.e26. doi: 10.1016/j.cell.2021.11.031. Epub 2021 Dec 14. Cell. 2021. PMID: 34910928 Free PMC article.

2

Multiscale analysis of the murine intestine for modeling human diseases.

Lyons J, Herring CA, Banerjee A, Simmons AJ, Lau KS. Lyons J, et al. Among authors: lau ks. Integr Biol (Camb). 2015 Jul;7(7):740-57. doi: 10.1039/c5ib00030k. Integr Biol (Camb). 2015. PMID: 26040649 Free PMC article.

3

Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo.

Simmons AJ, Banerjee A, McKinley ET, Scurrah CR, Herring CA, Gewin LS, Masuzaki R, Karp SJ, Franklin JL, Gerdes MJ, Irish JM, Coffey RJ, Lau KS. Simmons AJ, et al. Among authors: lau ks. Mol Syst Biol. 2015 Oct 30;11(10):835. doi: 10.15252/msb.20156282. Mol Syst Biol. 2015. PMID: 26519361 Free PMC article.

4

Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo.

Simmons AJ, Banerjee A, McKinley ET, Scurrah CR, Herring CA, Gewin LS, Masuzaki R, Karp SJ, Franklin JL, Gerdes MJ, Irish JM, Coffey RJ, Lau KS. Simmons AJ, et al. Among authors: lau ks. Mol Syst Biol. 2016 Aug 29;12(8):881. doi: 10.15252/msb.20167270. Mol Syst Biol. 2016. PMID: 27574014 Free PMC article.

5

Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks.

Simmons AJ, Scurrah CR, McKinley ET, Herring CA, Irish JM, Washington MK, Coffey RJ, Lau KS. Simmons AJ, et al. Among authors: lau ks. Sci Signal. 2016 Oct 11;9(449):rs11. doi: 10.1126/scisignal.aah4413. Sci Signal. 2016. PMID: 27729552 Free PMC article.

6

Deciphering tumor heterogeneity from FFPE tissues: Its promise and challenges.

Simmons AJ, Lau KS. Simmons AJ, et al. Among authors: lau ks. Mol Cell Oncol. 2016 Nov 18;4(1):e1260191. doi: 10.1080/23723556.2016.1260191. eCollection 2017. Mol Cell Oncol. 2016. PMID: 28197533 Free PMC article.

7

The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1.

Almohazey D, Lo YH, Vossler CV, Simmons AJ, Hsieh JJ, Bucar EB, Schumacher MA, Hamilton KE, Lau KS, Shroyer NF, Frey MR. Almohazey D, et al. Among authors: lau ks. Cell Death Differ. 2017 May;24(5):855-865. doi: 10.1038/cdd.2017.27. Epub 2017 Mar 17. Cell Death Differ. 2017. PMID: 28304405 Free PMC article.

8

Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity.

McKinley ET, Sui Y, Al-Kofahi Y, Millis BA, Tyska MJ, Roland JT, Santamaria-Pang A, Ohland CL, Jobin C, Franklin JL, Lau KS, Gerdes MJ, Coffey RJ. McKinley ET, et al. Among authors: lau ks. JCI Insight. 2017 Jun 2;2(11):e93487. doi: 10.1172/jci.insight.93487. eCollection 2017 Jun 2. JCI Insight. 2017. PMID: 28570279 Free PMC article.

9

Shear stress induces noncanonical autophagy in intestinal epithelial monolayers.

Kim SW, Ehrman J, Ahn MR, Kondo J, Lopez AAM, Oh YS, Kim XH, Crawley SW, Goldenring JR, Tyska MJ, Rericha EC, Lau KS. Kim SW, et al. Among authors: lau ks. Mol Biol Cell. 2017 Nov 1;28(22):3043-3056. doi: 10.1091/mbc.E17-01-0021. Epub 2017 Aug 30. Mol Biol Cell. 2017. PMID: 28855375 Free PMC article.

10

Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut.

Herring CA, Banerjee A, McKinley ET, Simmons AJ, Ping J, Roland JT, Franklin JL, Liu Q, Gerdes MJ, Coffey RJ, Lau KS. Herring CA, et al. Among authors: lau ks. Cell Syst. 2018 Jan 24;6(1):37-51.e9. doi: 10.1016/j.cels.2017.10.012. Epub 2017 Nov 15. Cell Syst. 2018. PMID: 29153838 Free PMC article.

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