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Mechanistic basis for ubiquitin modulation of a protein energy landscape.
Carroll EC, Latorraca NR, Lindner JM, Maguire BC, Pelton JG, Marqusee S. Carroll EC, et al. Among authors: latorraca nr. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2025126118. doi: 10.1073/pnas.2025126118. Proc Natl Acad Sci U S A. 2021. PMID: 33723075 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 36782752
Negative allosteric modulation of the glucagon receptor by RAMP2.
Krishna Kumar K, O'Brien ES, Habrian CH, Latorraca NR, Wang H, Tuneew I, Montabana E, Marqusee S, Hilger D, Isacoff EY, Mathiesen JM, Kobilka BK. Krishna Kumar K, et al. Among authors: latorraca nr. Cell. 2023 Mar 30;186(7):1465-1477.e18. doi: 10.1016/j.cell.2023.02.028. Cell. 2023. PMID: 37001505 Free PMC article.
Gi- and Gs-coupled GPCRs show different modes of G-protein binding.
Van Eps N, Altenbach C, Caro LN, Latorraca NR, Hollingsworth SA, Dror RO, Ernst OP, Hubbell WL. Van Eps N, et al. Among authors: latorraca nr. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2383-2388. doi: 10.1073/pnas.1721896115. Epub 2018 Feb 20. Proc Natl Acad Sci U S A. 2018. PMID: 29463720 Free PMC article.
Diverse GPCRs exhibit conserved water networks for stabilization and activation.
Venkatakrishnan AJ, Ma AK, Fonseca R, Latorraca NR, Kelly B, Betz RM, Asawa C, Kobilka BK, Dror RO. Venkatakrishnan AJ, et al. Among authors: latorraca nr. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3288-3293. doi: 10.1073/pnas.1809251116. Epub 2019 Feb 6. Proc Natl Acad Sci U S A. 2019. PMID: 30728297 Free PMC article.
GPCR Dynamics: Structures in Motion.
Latorraca NR, Venkatakrishnan AJ, Dror RO. Latorraca NR, et al. Chem Rev. 2017 Jan 11;117(1):139-155. doi: 10.1021/acs.chemrev.6b00177. Epub 2016 Sep 13. Chem Rev. 2017. PMID: 27622975 Free article. Review.
34 results