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Dynamic structural determinants underlie the neurotoxicity of the N-terminal tau 26-44 peptide in Alzheimer's disease and other human tauopathies.
Perini G, Ciasca G, Minelli E, Papi M, Palmieri V, Maulucci G, Nardini M, Latina V, Corsetti V, Florenzano F, Calissano P, De Spirito M, Amadoro G. Perini G, et al. Among authors: latina v. Int J Biol Macromol. 2019 Dec 1;141:278-289. doi: 10.1016/j.ijbiomac.2019.08.220. Epub 2019 Aug 27. Int J Biol Macromol. 2019. PMID: 31470053
Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies.
Florenzano F, Veronica C, Ciasca G, Ciotti MT, Pittaluga A, Olivero G, Feligioni M, Iannuzzi F, Latina V, Maria Sciacca MF, Sinopoli A, Milardi D, Pappalardo G, Marco S, Papi M, Atlante A, Bobba A, Borreca A, Calissano P, Amadoro G. Florenzano F, et al. Among authors: latina v. Oncotarget. 2017 Apr 22;8(39):64745-64778. doi: 10.18632/oncotarget.17371. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029390 Free PMC article.
AD-Related N-Terminal Truncated Tau Is Sufficient to Recapitulate In Vivo the Early Perturbations of Human Neuropathology: Implications for Immunotherapy.
Borreca A, Latina V, Corsetti V, Middei S, Piccinin S, Della Valle F, Bussani R, Ammassari-Teule M, Nisticò R, Calissano P, Amadoro G. Borreca A, et al. Among authors: latina v. Mol Neurobiol. 2018 Oct;55(10):8124-8153. doi: 10.1007/s12035-018-0974-3. Epub 2018 Mar 5. Mol Neurobiol. 2018. PMID: 29508283
Impaired adult neurogenesis is an early event in Alzheimer's disease neurodegeneration, mediated by intracellular Aβ oligomers.
Scopa C, Marrocco F, Latina V, Ruggeri F, Corvaglia V, La Regina F, Ammassari-Teule M, Middei S, Amadoro G, Meli G, Scardigli R, Cattaneo A. Scopa C, et al. Among authors: latina v. Cell Death Differ. 2020 Mar;27(3):934-948. doi: 10.1038/s41418-019-0409-3. Epub 2019 Oct 7. Cell Death Differ. 2020. PMID: 31591472 Free PMC article.
30 results