Latacz G - Search Results

1

New, Eco-Friendly Method for Synthesis of 3-Chlorophenyl and 1,1'-Biphenyl Piperazinylhexyl Trazodone Analogues with Dual 5-HT_1A/5-HT₇ Affinity and Its Antidepressant-like Activity.

Zaręba P, Partyka A, Latacz G, Satała G, Zajdel P, Jaśkowska J. Zaręba P, et al. Among authors: latacz g. Molecules. 2022 Oct 26;27(21):7270. doi: 10.3390/molecules27217270. Molecules. 2022. PMID: 36364104 Free PMC article.

2

Rational design in search for 5-phenylhydantoin selective 5-HT7R antagonists. Molecular modeling, synthesis and biological evaluation.

Kucwaj-Brysz K, Warszycki D, Podlewska S, Witek J, Witek K, González Izquierdo A, Satała G, Loza MI, Lubelska A, Latacz G, Bojarski AJ, Castro M, Kieć-Kononowicz K, Handzlik J. Kucwaj-Brysz K, et al. Among authors: latacz g. Eur J Med Chem. 2016 Apr 13;112:258-269. doi: 10.1016/j.ejmech.2016.02.024. Epub 2016 Feb 9. Eur J Med Chem. 2016. PMID: 26900658

3

Low-basicity 5-HT₇ Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol.

Hogendorf AS, Hogendorf A, Kurczab R, Satała G, Lenda T, Walczak M, Latacz G, Handzlik J, Kieć-Kononowicz K, Wierońska JM, Woźniak M, Cieślik P, Bugno R, Staroń J, Bojarski AJ. Hogendorf AS, et al. Among authors: latacz g. Sci Rep. 2017 May 4;7(1):1444. doi: 10.1038/s41598-017-00822-4. Sci Rep. 2017. PMID: 28473721 Free PMC article.

4

In the search for a lead structure among series of potent and selective hydantoin 5-HT₇ R agents: The drug-likeness in vitro study.

Latacz G, Lubelska A, Jastrzębska-Więsek M, Partyka A, Sobiło A, Olejarz A, Kucwaj-Brysz K, Satała G, Bojarski AJ, Wesołowska A, Kieć-Kononowicz K, Handzlik J. Latacz G, et al. Chem Biol Drug Des. 2017 Dec;90(6):1295-1306. doi: 10.1111/cbdd.13106. Epub 2017 Oct 3. Chem Biol Drug Des. 2017. PMID: 28886235

5

Study on the effect of EMD386088, a 5-HT₆ receptor partial agonist, in enhancing the anti-immobility action of some antidepressants in rats.

Jastrzębska-Więsek M, Siwek A, Partyka A, Kołaczkowski M, Walczak M, Smolik M, Latacz G, Kieć-Kononowicz K, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: latacz g. Naunyn Schmiedebergs Arch Pharmacol. 2018 Jan;391(1):37-49. doi: 10.1007/s00210-017-1431-y. Epub 2017 Oct 27. Naunyn Schmiedebergs Arch Pharmacol. 2018. PMID: 29079874 Free PMC article.

6

Selenazolinium Salts as "Small Molecule Catalysts" with High Potency against ESKAPE Bacterial Pathogens.

Witek K, Nasim MJ, Bischoff M, Gaupp R, Arsenyan P, Vasiljeva J, Marć MA, Olejarz A, Latacz G, Kieć-Kononowicz K, Handzlik J, Jacob C. Witek K, et al. Among authors: latacz g. Molecules. 2017 Dec 8;22(12):2174. doi: 10.3390/molecules22122174. Molecules. 2017. PMID: 29292789 Free PMC article.

7

MF-8, a novel promising arylpiperazine-hydantoin based 5-HT₇ receptor antagonist: In vitro drug-likeness studies and in vivo pharmacological evaluation.

Latacz G, Lubelska A, Jastrzębska-Więsek M, Partyka A, Kucwaj-Brysz K, Wesołowska A, Kieć-Kononowicz K, Handzlik J. Latacz G, et al. Bioorg Med Chem Lett. 2018 Mar 1;28(5):878-883. doi: 10.1016/j.bmcl.2018.02.003. Epub 2018 Feb 3. Bioorg Med Chem Lett. 2018. PMID: 29439902

8

Novel naphthyloxy derivatives - Potent histamine H₃ receptor ligands. Synthesis and pharmacological evaluation.

Łażewska D, Kaleta M, Hagenow S, Mogilski S, Latacz G, Karcz T, Lubelska A, Honkisz E, Handzlik J, Reiner D, Satała G, Filipek B, Stark H, Kieć-Kononowicz K. Łażewska D, et al. Among authors: latacz g. Bioorg Med Chem. 2018 May 15;26(9):2573-2585. doi: 10.1016/j.bmc.2018.04.023. Epub 2018 Apr 11. Bioorg Med Chem. 2018. PMID: 29681486

9

The role of aryl-topology in balancing between selective and dual 5-HT₇R/5-HT_1A actions of 3,5-substituted hydantoins.

Kucwaj-Brysz K, Kurczab R, Żesławska E, Lubelska A, Marć MA, Latacz G, Satała G, Nitek W, Kieć-Kononowicz K, Handzlik J. Kucwaj-Brysz K, et al. Among authors: latacz g. Medchemcomm. 2018 May 8;9(6):1033-1044. doi: 10.1039/c8md00168e. eCollection 2018 Jun 1. Medchemcomm. 2018. PMID: 30108992 Free PMC article.

10

Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT₆ Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In Vivo.

Kurczab R, Ali W, Łażewska D, Kotańska M, Jastrzębska-Więsek M, Satała G, Więcek M, Lubelska A, Latacz G, Partyka A, Starek M, Dąbrowska M, Wesołowska A, Jacob C, Kieć-Kononowicz K, Handzlik J. Kurczab R, et al. Among authors: latacz g. Molecules. 2018 Oct 3;23(10):2529. doi: 10.3390/molecules23102529. Molecules. 2018. PMID: 30282913 Free PMC article.

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