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Serotonin 5-HT6 Receptor Ligands and Butyrylcholinesterase Inhibitors Displaying Antioxidant Activity-Design, Synthesis and Biological Evaluation of Multifunctional Agents against Alzheimer's Disease.
Więckowski K, Szałaj N, Gryzło B, Wichur T, Góral I, Sługocka E, Sniecikowska J, Latacz G, Siwek A, Godyń J, Bucki A, Kołaczkowski M, Więckowska A. Więckowski K, et al. Among authors: latacz g. Int J Mol Sci. 2022 Aug 21;23(16):9443. doi: 10.3390/ijms23169443. Int J Mol Sci. 2022. PMID: 36012707 Free PMC article.
(2-Arylethenyl)-1,3,5-triazin-2-amines as a novel histamine H4 receptor ligands.
Kamińska K, Ziemba J, Ner J, Schwed JS, Łażewska D, Więcek M, Karcz T, Olejarz A, Latacz G, Kuder K, Kottke T, Zygmunt M, Sapa J, Karolak-Wojciechowska J, Stark H, Kieć-Kononowicz K. Kamińska K, et al. Among authors: latacz g. Eur J Med Chem. 2015 Oct 20;103:238-51. doi: 10.1016/j.ejmech.2015.08.014. Epub 2015 Aug 10. Eur J Med Chem. 2015. PMID: 26360048
Biphenyloxy-alkyl-piperidine and azepane derivatives as histamine H3 receptor ligands.
Łażewska D, Kaleta M, Schwed JS, Karcz T, Mogilski S, Latacz G, Olejarz A, Siwek A, Kubacka M, Lubelska A, Honkisz E, Handzlik J, Filipek B, Stark H, Kieć-Kononowicz K. Łażewska D, et al. Among authors: latacz g. Bioorg Med Chem. 2017 Oct 15;25(20):5341-5354. doi: 10.1016/j.bmc.2017.07.058. Epub 2017 Jul 29. Bioorg Med Chem. 2017. PMID: 28797771
Study on the effect of EMD386088, a 5-HT6 receptor partial agonist, in enhancing the anti-immobility action of some antidepressants in rats.
Jastrzębska-Więsek M, Siwek A, Partyka A, Kołaczkowski M, Walczak M, Smolik M, Latacz G, Kieć-Kononowicz K, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: latacz g. Naunyn Schmiedebergs Arch Pharmacol. 2018 Jan;391(1):37-49. doi: 10.1007/s00210-017-1431-y. Epub 2017 Oct 27. Naunyn Schmiedebergs Arch Pharmacol. 2018. PMID: 29079874 Free PMC article.
Novel Multitarget-Directed Ligands Aiming at Symptoms and Causes of Alzheimer's Disease.
Więckowska A, Wichur T, Godyń J, Bucki A, Marcinkowska M, Siwek A, Więckowski K, Zaręba P, Knez D, Głuch-Lutwin M, Kazek G, Latacz G, Mika K, Kołaczkowski M, Korabecny J, Soukup O, Benkova M, Kieć-Kononowicz K, Gobec S, Malawska B. Więckowska A, et al. Among authors: latacz g. ACS Chem Neurosci. 2018 May 16;9(5):1195-1214. doi: 10.1021/acschemneuro.8b00024. Epub 2018 Feb 13. ACS Chem Neurosci. 2018. PMID: 29384656
Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H3R ligands.
Szczepańska K, Karcz T, Mogilski S, Siwek A, Kuder KJ, Latacz G, Kubacka M, Hagenow S, Lubelska A, Olejarz A, Kotańska M, Sadek B, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: latacz g. Eur J Med Chem. 2018 May 25;152:223-234. doi: 10.1016/j.ejmech.2018.04.043. Epub 2018 Apr 25. Eur J Med Chem. 2018. PMID: 29723785
Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT₆ Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In Vivo.
Kurczab R, Ali W, Łażewska D, Kotańska M, Jastrzębska-Więsek M, Satała G, Więcek M, Lubelska A, Latacz G, Partyka A, Starek M, Dąbrowska M, Wesołowska A, Jacob C, Kieć-Kononowicz K, Handzlik J. Kurczab R, et al. Among authors: latacz g. Molecules. 2018 Oct 3;23(10):2529. doi: 10.3390/molecules23102529. Molecules. 2018. PMID: 30282913 Free PMC article.
Optimization and preclinical evaluation of novel histamine H3receptor ligands: Acetyl and propionyl phenoxyalkyl piperazine derivatives.
Szczepańska K, Karcz T, Kotańska M, Siwek A, Kuder KJ, Latacz G, Mogilski S, Hagenow S, Lubelska A, Sobolewski M, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: latacz g. Bioorg Med Chem. 2018 Dec 15;26(23-24):6056-6066. doi: 10.1016/j.bmc.2018.11.010. Epub 2018 Nov 10. Bioorg Med Chem. 2018. PMID: 30448256
121 results