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Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Osterman IA, Wieland M, Maviza TP, Lashkevich KA, Lukianov DA, Komarova ES, Zakalyukina YV, Buschauer R, Shiriaev DI, Leyn SA, Zlamal JE, Biryukov MV, Skvortsov DA, Tashlitsky VN, Polshakov VI, Cheng J, Polikanov YS, Bogdanov AA, Osterman AL, Dmitriev SE, Beckmann R, Dontsova OA, Wilson DN, Sergiev PV. Osterman IA, et al. Among authors: lashkevich ka. Nat Chem Biol. 2020 Oct;16(10):1071-1077. doi: 10.1038/s41589-020-0578-x. Epub 2020 Jun 29. Nat Chem Biol. 2020. PMID: 32601485
A Solitary Stalled 80S Ribosome Prevents mRNA Recruitment to Stress Granules.
Fedorovskiy AG, Burakov AV, Terenin IM, Bykov DA, Lashkevich KA, Popenko VI, Makarova NE, Sorokin II, Sukhinina AP, Prassolov VS, Ivanov PV, Dmitriev SE. Fedorovskiy AG, et al. Among authors: lashkevich ka. Biochemistry (Mosc). 2023 Nov;88(11):1786-1799. doi: 10.1134/S000629792311010X. Biochemistry (Mosc). 2023. PMID: 38105199
Monitoring integrated stress response in live Drosophila.
Lidsky PV, Yuan J, Lashkevich KA, Dmitriev SE, Andino R. Lidsky PV, et al. Among authors: lashkevich ka. bioRxiv [Preprint]. 2023 Jul 14:2023.07.13.548942. doi: 10.1101/2023.07.13.548942. bioRxiv. 2023. PMID: 37502856 Free PMC article. Preprint.