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Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders.
Pastor M, Fernández-Calle R, Di Geronimo B, Vicente-Rodríguez M, Zapico JM, Gramage E, Coderch C, Pérez-García C, Lasek AW, Puchades-Carrasco L, Pineda-Lucena A, de Pascual-Teresa B, Herradón G, Ramos A. Pastor M, et al. Among authors: lasek aw. Eur J Med Chem. 2018 Jan 20;144:318-329. doi: 10.1016/j.ejmech.2017.11.080. Epub 2017 Nov 28. Eur J Med Chem. 2018. PMID: 29275231 Free PMC article.
Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol.
Fernández-Calle R, Vicente-Rodríguez M, Pastor M, Gramage E, Di Geronimo B, Zapico JM, Coderch C, Pérez-García C, Lasek AW, de Pascual-Teresa B, Ramos A, Herradón G. Fernández-Calle R, et al. Among authors: lasek aw. Neuropharmacology. 2018 Jul 15;137:86-95. doi: 10.1016/j.neuropharm.2018.04.027. Epub 2018 May 9. Neuropharmacology. 2018. PMID: 29753117 Free PMC article.
Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer.
Lu Y, Gutgesell LM, Xiong R, Zhao J, Li Y, Rosales CI, Hollas M, Shen Z, Gordon-Blake J, Dye K, Wang Y, Lee S, Chen H, He D, Dubrovyskyii O, Zhao H, Huang F, Lasek AW, Tonetti DA, Thatcher GRJ. Lu Y, et al. Among authors: lasek aw. J Med Chem. 2019 Dec 26;62(24):11301-11323. doi: 10.1021/acs.jmedchem.9b01580. Epub 2019 Dec 10. J Med Chem. 2019. PMID: 31746603 Free PMC article.
Inhibition of RPTPβ/ζ reduces chronic ethanol intake in adolescent mice and modulates ethanol effects on hippocampal neurogenesis and glial responses in a sex-dependent manner.
Galán-Llario M, Rodríguez-Zapata M, Fontán-Baselga T, Gramage E, Vicente-Rodríguez M, Zapico JM, de Pascual-Teresa B, Lasek AW, Herradón G. Galán-Llario M, et al. Among authors: lasek aw. Neuropharmacology. 2023 Apr 1;227:109438. doi: 10.1016/j.neuropharm.2023.109438. Epub 2023 Jan 24. Neuropharmacology. 2023. PMID: 36706907 Free PMC article.
68 results