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Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion.
Wang X, Istvanffy R, Ye L, Teller S, Laschinger M, Diakopoulos KN, Görgülü K, Li Q, Ren L, Jäger C, Steiger K, Muckenhuber A, Vilne B, Çifcibaşı K, Reyes CM, Yurteri Ü, Kießler M, Gürçınar IH, Sugden M, Yıldızhan SE, Sezerman OU, Çilingir S, Süyen G, Reichert M, Schmid RM, Bärthel S, Oellinger R, Krüger A, Rad R, Saur D, Algül H, Friess H, Lesina M, Ceyhan GO, Demir IE. Wang X, et al. Among authors: laschinger m. J Clin Invest. 2023 Nov 1;133(21):e166333. doi: 10.1172/JCI166333. J Clin Invest. 2023. PMID: 37607005 Free PMC article.
The severity of neural invasion is associated with shortened survival in colon cancer.
Liebl F, Demir IE, Rosenberg R, Boldis A, Yildiz E, Kujundzic K, Kehl T, Dischl D, Schuster T, Maak M, Becker K, Langer R, Laschinger M, Friess H, Ceyhan GO. Liebl F, et al. Among authors: laschinger m. Clin Cancer Res. 2013 Jan 1;19(1):50-61. doi: 10.1158/1078-0432.CCR-12-2392. Epub 2012 Nov 12. Clin Cancer Res. 2013. PMID: 23147996
Activated Schwann cells in pancreatic cancer are linked to analgesia via suppression of spinal astroglia and microglia.
Demir IE, Tieftrunk E, Schorn S, Saricaoglu ÖC, Pfitzinger PL, Teller S, Wang K, Waldbaur C, Kurkowski MU, Wörmann SM, Shaw VE, Kehl T, Laschinger M, Costello E, Algül H, Friess H, Ceyhan GO. Demir IE, et al. Among authors: laschinger m. Gut. 2016 Jun;65(6):1001-14. doi: 10.1136/gutjnl-2015-309784. Epub 2016 Jan 13. Gut. 2016. PMID: 26762195
BRG1 promotes hepatocarcinogenesis by regulating proliferation and invasiveness.
Kaufmann B, Wang B, Zhong S, Laschinger M, Patil P, Lu M, Assfalg V, Cheng Z, Friess H, Hüser N, von Figura G, Hartmann D. Kaufmann B, et al. Among authors: laschinger m. PLoS One. 2017 Jul 12;12(7):e0180225. doi: 10.1371/journal.pone.0180225. eCollection 2017. PLoS One. 2017. PMID: 28700662 Free PMC article.
43 results