Larsson R - Search Results

1

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments.

Zhang X, Fryknäs M, Hernlund E, Fayad W, De Milito A, Olofsson MH, Gogvadze V, Dang L, Påhlman S, Schughart LA, Rickardson L, D'Arcy P, Gullbo J, Nygren P, Larsson R, Linder S. Zhang X, et al. Among authors: larsson r. Nat Commun. 2014;5:3295. doi: 10.1038/ncomms4295. Nat Commun. 2014. PMID: 24548894 Free PMC article.

2

Identification of agents that induce apoptosis of multicellular tumour spheroids: enrichment for mitotic inhibitors with hydrophobic properties.

Fayad W, Rickardson L, Haglund C, Olofsson MH, D'Arcy P, Larsson R, Linder S, Fryknäs M. Fayad W, et al. Among authors: larsson r. Chem Biol Drug Des. 2011 Oct;78(4):547-57. doi: 10.1111/j.1747-0285.2011.01170.x. Epub 2011 Jul 29. Chem Biol Drug Des. 2011. PMID: 21726416

3

Iron chelators target both proliferating and quiescent cancer cells.

Fryknäs M, Zhang X, Bremberg U, Senkowski W, Olofsson MH, Brandt P, Persson I, D'Arcy P, Gullbo J, Nygren P, Schughart LK, Linder S, Larsson R. Fryknäs M, et al. Among authors: larsson r. Sci Rep. 2016 Dec 7;6:38343. doi: 10.1038/srep38343. Sci Rep. 2016. PMID: 27924826 Free PMC article.

4

Pharmacological profiling of novel non-COX-inhibiting indole-pyran analogues of etodolac reveals high solid tumour activity of SDX-308 in vitro.

Lindhagen E, Rickardson L, Elliott G, Leoni L, Nygren P, Larsson R, Aleskog A. Lindhagen E, et al. Among authors: larsson r. Invest New Drugs. 2007 Aug;25(4):297-303. doi: 10.1007/s10637-007-9049-4. Epub 2007 Apr 18. Invest New Drugs. 2007. PMID: 17440681

5

The fluorometric microculture cytotoxicity assay.

Lindhagen E, Nygren P, Larsson R. Lindhagen E, et al. Among authors: larsson r. Nat Protoc. 2008;3(8):1364-9. doi: 10.1038/nprot.2008.114. Nat Protoc. 2008. PMID: 18714304

6

Identification of a novel topoisomerase inhibitor effective in cells overexpressing drug efflux transporters.

Fayad W, Fryknäs M, Brnjic S, Olofsson MH, Larsson R, Linder S. Fayad W, et al. Among authors: larsson r. PLoS One. 2009 Oct 2;4(10):e7238. doi: 10.1371/journal.pone.0007238. PLoS One. 2009. PMID: 19798419 Free PMC article.

7

Phenotype-based drug screening in primary ovarian carcinoma cultures identifies intracellular iron depletion as a promising strategy for cancer treatment.

Gullbo J, Fryknäs M, Rickardson L, Darcy P, Hägg M, Wickström M, Hassan S, Westman G, Brnjic S, Nygren P, Linder S, Larsson R. Gullbo J, et al. Among authors: larsson r. Biochem Pharmacol. 2011 Jul 15;82(2):139-47. doi: 10.1016/j.bcp.2011.04.003. Epub 2011 Apr 22. Biochem Pharmacol. 2011. PMID: 21531212 Free article.

8

Inhibition of proteasome deubiquitinating activity as a new cancer therapy.

D'Arcy P, Brnjic S, Olofsson MH, Fryknäs M, Lindsten K, De Cesare M, Perego P, Sadeghi B, Hassan M, Larsson R, Linder S. D'Arcy P, et al. Among authors: larsson r. Nat Med. 2011 Nov 6;17(12):1636-40. doi: 10.1038/nm.2536. Nat Med. 2011. PMID: 22057347

9

The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy.

Hernlund E, Olofsson MH, Fayad W, Fryknäs M, Lesiak-Mieczkowska K, Zhang X, Brnjic S, Schmidt V, D'Arcy P, Sjöblom T, De Milito A, Larsson R, Linder S. Hernlund E, et al. Among authors: larsson r. Eur J Cancer. 2012 Feb;48(3):396-406. doi: 10.1016/j.ejca.2011.11.013. Epub 2011 Dec 7. Eur J Cancer. 2012. PMID: 22154651

10

Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system.

Karlsson H, Fryknäs M, Larsson R, Nygren P. Karlsson H, et al. Among authors: larsson r. Exp Cell Res. 2012 Aug 1;318(13):1577-85. doi: 10.1016/j.yexcr.2012.03.026. Epub 2012 Apr 2. Exp Cell Res. 2012. PMID: 22487097

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

522 results

Search Page