Larsson LG - Search Results

1

MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner.

Castell A, Yan Q, Fawkner K, Bazzar W, Zhang F, Wickström M, Alzrigat M, Franco M, Krona C, Cameron DP, Dyberg C, Olsen TK, Verschut V, Schmidt L, Lim SY, Mahmoud L, Hydbring P, Lehmann S, Baranello L, Nelander S, Johnsen JI, Larsson LG. Castell A, et al. Among authors: larsson lg. Cancer Res Commun. 2022 Mar 31;2(3):182-201. doi: 10.1158/2767-9764.CRC-21-0019. eCollection 2022 Mar. Cancer Res Commun. 2022. PMID: 36874405 Free PMC article.

2

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription.

von der Lehr N, Johansson S, Wu S, Bahram F, Castell A, Cetinkaya C, Hydbring P, Weidung I, Nakayama K, Nakayama KI, Söderberg O, Kerppola TK, Larsson LG. von der Lehr N, et al. Among authors: larsson lg. Mol Cell. 2003 May;11(5):1189-200. doi: 10.1016/s1097-2765(03)00193-x. Mol Cell. 2003. PMID: 12769844 Free article.

3

Mad 1 inhibits cell growth and proliferation but does not promote differentiation or overall survival in human U-937 monoblasts.

Hultquist A, Cetinkaya C, Wu S, Castell A, Erlandsson A, Larsson LG. Hultquist A, et al. Among authors: larsson lg. Mol Cancer Res. 2004 Aug;2(8):464-76. Mol Cancer Res. 2004. PMID: 15328373

4

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.

Arabi A, Wu S, Ridderstråle K, Bierhoff H, Shiue C, Fatyol K, Fahlén S, Hydbring P, Söderberg O, Grummt I, Larsson LG, Wright AP. Arabi A, et al. Among authors: larsson lg. Nat Cell Biol. 2005 Mar;7(3):303-10. doi: 10.1038/ncb1225. Epub 2005 Feb 20. Nat Cell Biol. 2005. PMID: 15723053

5

Direct observation of individual endogenous protein complexes in situ by proximity ligation.

Söderberg O, Gullberg M, Jarvius M, Ridderstråle K, Leuchowius KJ, Jarvius J, Wester K, Hydbring P, Bahram F, Larsson LG, Landegren U. Söderberg O, et al. Among authors: larsson lg. Nat Methods. 2006 Dec;3(12):995-1000. doi: 10.1038/nmeth947. Epub 2006 Oct 29. Nat Methods. 2006. PMID: 17072308

6

TGF-beta enforces senescence in Myc-transformed hematopoietic tumor cells through induction of Mad1 and repression of Myc activity.

Wu S, Hultquist A, Hydbring P, Cetinkaya C, Oberg F, Larsson LG. Wu S, et al. Among authors: larsson lg. Exp Cell Res. 2009 Nov 1;315(18):3099-111. doi: 10.1016/j.yexcr.2009.09.009. Epub 2009 Sep 17. Exp Cell Res. 2009. PMID: 19766114

7

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation.

Hydbring P, Bahram F, Su Y, Tronnersjö S, Högstrand K, von der Lehr N, Sharifi HR, Lilischkis R, Hein N, Wu S, Vervoorts J, Henriksson M, Grandien A, Lüscher B, Larsson LG. Hydbring P, et al. Among authors: larsson lg. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):58-63. doi: 10.1073/pnas.0900121106. Epub 2009 Dec 4. Proc Natl Acad Sci U S A. 2010. PMID: 19966300 Free PMC article.

8

Myc is required for activation of the ATM-dependent checkpoints in response to DNA damage.

Guerra L, Albihn A, Tronnersjö S, Yan Q, Guidi R, Stenerlöw B, Sterzenbach T, Josenhans C, Fox JG, Schauer DB, Thelestam M, Larsson LG, Henriksson M, Frisan T. Guerra L, et al. Among authors: larsson lg. PLoS One. 2010 Jan 27;5(1):e8924. doi: 10.1371/journal.pone.0008924. PLoS One. 2010. PMID: 20111719 Free PMC article.

9

Cdk2: a key regulator of the senescence control function of Myc.

Hydbring P, Larsson LG. Hydbring P, et al. Among authors: larsson lg. Aging (Albany NY). 2010 Apr;2(4):244-50. doi: 10.18632/aging.100140. Aging (Albany NY). 2010. PMID: 20445224 Free PMC article. Review.

10

Tipping the balance: Cdk2 enables Myc to suppress senescence.

Hydbring P, Larsson LG. Hydbring P, et al. Among authors: larsson lg. Cancer Res. 2010 Sep 1;70(17):6687-91. doi: 10.1158/0008-5472.CAN-10-1383. Epub 2010 Aug 16. Cancer Res. 2010. PMID: 20713526 Review.

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