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The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase.
Larsen ISB, Povolo L, Zhou L, Tian W, Mygind KJ, Hintze J, Jiang C, Hartill V, Prescott K, Johnson CA, Mullegama SV, McConkie-Rosell A, McDonald M, Hansen L, Vakhrushev SY, Schjoldager KT, Clausen H, Worzfeld T, Joshi HJ, Halim A. Larsen ISB, et al. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2302584120. doi: 10.1073/pnas.2302584120. Epub 2023 May 15. Proc Natl Acad Sci U S A. 2023. PMID: 37186866 Free PMC article.
Discovery of a nucleocytoplasmic O-mannose glycoproteome in yeast.
Halim A, Larsen IS, Neubert P, Joshi HJ, Petersen BL, Vakhrushev SY, Strahl S, Clausen H. Halim A, et al. Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15648-53. doi: 10.1073/pnas.1511743112. Epub 2015 Dec 7. Proc Natl Acad Sci U S A. 2015. PMID: 26644575 Free PMC article.
Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins.
Larsen ISB, Narimatsu Y, Joshi HJ, Siukstaite L, Harrison OJ, Brasch J, Goodman KM, Hansen L, Shapiro L, Honig B, Vakhrushev SY, Clausen H, Halim A. Larsen ISB, et al. Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11163-11168. doi: 10.1073/pnas.1708319114. Epub 2017 Oct 2. Proc Natl Acad Sci U S A. 2017. PMID: 28973932 Free PMC article.
Multiple distinct O-Mannosylation pathways in eukaryotes.
Larsen ISB, Narimatsu Y, Clausen H, Joshi HJ, Halim A. Larsen ISB, et al. Curr Opin Struct Biol. 2019 Jun;56:171-178. doi: 10.1016/j.sbi.2019.03.003. Epub 2019 Apr 15. Curr Opin Struct Biol. 2019. PMID: 30999272 Review.
Mapping the O-Mannose Glycoproteome in Saccharomyces cerevisiae.
Neubert P, Halim A, Zauser M, Essig A, Joshi HJ, Zatorska E, Larsen IS, Loibl M, Castells-Ballester J, Aebi M, Clausen H, Strahl S. Neubert P, et al. Mol Cell Proteomics. 2016 Apr;15(4):1323-37. doi: 10.1074/mcp.M115.057505. Epub 2016 Jan 13. Mol Cell Proteomics. 2016. PMID: 26764011 Free PMC article.
12 results