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Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism.
Jensen BAH, Holm JB, Larsen IS, von Burg N, Derer S, Sonne SB, Pærregaard SI, Damgaard MV, Indrelid SA, Rivollier A, Agrinier AL, Sulek K, Arnoldussen YJ, Fjære E, Marette A, Angell IL, Rudi K, Treebak JT, Madsen L, Åkesson CP, Agace W, Sina C, Kleiveland CR, Kristiansen K, Lea TE. Jensen BAH, et al. Among authors: larsen is. Nat Commun. 2021 Feb 17;12(1):1093. doi: 10.1038/s41467-021-21408-9. Nat Commun. 2021. PMID: 33597537 Free PMC article.
Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice.
Larsen IS, Fritzen AM, Carl CS, Agerholm M, Damgaard MTF, Holm JB, Marette A, Nordkild P, Kiens B, Kristiansen K, Wehkamp J, Jensen BAH. Larsen IS, et al. Am J Physiol Endocrinol Metab. 2019 Jul 1;317(1):E42-E52. doi: 10.1152/ajpendo.00019.2019. Epub 2019 Mar 12. Am J Physiol Endocrinol Metab. 2019. PMID: 30860877 Free article.
Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis.
Larsen IS, Jensen BAH, Bonazzi E, Choi BSY, Kristensen NN, Schmidt EGW, Süenderhauf A, Morin L, Olsen PB, Hansen LBS, Schröder T, Sina C, Chassaing B, Marette A. Larsen IS, et al. Gut Microbes. 2021 Jan-Dec;13(1):1988836. doi: 10.1080/19490976.2021.1988836. Gut Microbes. 2021. PMID: 34693864 Free PMC article.
Human Beta Defensin 2 Ameliorated Alcohol-Associated Liver Disease in Mice.
Warner JB, Larsen IS, Hardesty JE, Song YL, Warner DR, McClain CJ, Sun R, Deng Z, Jensen BAH, Kirpich IA. Warner JB, et al. Among authors: larsen is. Front Physiol. 2022 Jan 27;12:812882. doi: 10.3389/fphys.2021.812882. eCollection 2021. Front Physiol. 2022. PMID: 35153819 Free PMC article.
Experimental diets dictate the metabolic benefits of probiotics in obesity.
Larsen IS, Choi BS, Föh B, Kristensen NN, Ouellette A, Haller RF, Olsen PB, Saulnier D, Sina C, Jensen BAH, Marette A. Larsen IS, et al. Gut Microbes. 2023 Jan-Dec;15(1):2192547. doi: 10.1080/19490976.2023.2192547. Gut Microbes. 2023. PMID: 36945120 Free PMC article.
Bacillus velezensis DSM 33864 reduces Clostridioides difficile colonization without disturbing commensal gut microbiota composition.
Larsen IS, Chenaux M, Collins FWJ, Mandic A, Hansen LBS, Lauridsen CAS, Haller RF, Elvig-Jørgensen S, Horwell E, Christiansen J, Silva A, Vehreschild MJGT, Cutting SM, Roggenbuck-Wedemeyer M, Kristensen NN. Larsen IS, et al. Sci Rep. 2023 Sep 11;13(1):14941. doi: 10.1038/s41598-023-42128-8. Sci Rep. 2023. PMID: 37696924 Free PMC article.
The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase.
Larsen ISB, Povolo L, Zhou L, Tian W, Mygind KJ, Hintze J, Jiang C, Hartill V, Prescott K, Johnson CA, Mullegama SV, McConkie-Rosell A, McDonald M, Hansen L, Vakhrushev SY, Schjoldager KT, Clausen H, Worzfeld T, Joshi HJ, Halim A. Larsen ISB, et al. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2302584120. doi: 10.1073/pnas.2302584120. Epub 2023 May 15. Proc Natl Acad Sci U S A. 2023. PMID: 37186866 Free PMC article.
22 results