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A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization.
Zampetidis CP, Galanos P, Angelopoulou A, Zhu Y, Polyzou A, Karamitros T, Kotsinas A, Lagopati N, Mourkioti I, Mirzazadeh R, Polyzos A, Garnerone S, Mizi A, Gusmao EG, Sofiadis K, Gál Z, Larsen DH, Pefani DE, Demaria M, Tsirigos A, Crosetto N, Maya-Mendoza A, Papaspyropoulos A, Evangelou K, Bartek J, Papantonis A, Gorgoulis VG. Zampetidis CP, et al. Among authors: larsen dh. Mol Cell. 2021 Dec 2;81(23):4907-4923.e8. doi: 10.1016/j.molcel.2021.10.017. Epub 2021 Nov 17. Mol Cell. 2021. PMID: 34793711 Free article.
HCLK2 is required for activity of the DNA damage response kinase ATR.
Rendtlew Danielsen JM, Larsen DH, Schou KB, Freire R, Falck J, Bartek J, Lukas J. Rendtlew Danielsen JM, et al. Among authors: larsen dh. J Biol Chem. 2009 Feb 13;284(7):4140-7. doi: 10.1074/jbc.M808174200. Epub 2008 Dec 19. J Biol Chem. 2009. PMID: 19097996 Free article.
The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage.
Larsen DH, Poinsignon C, Gudjonsson T, Dinant C, Payne MR, Hari FJ, Rendtlew Danielsen JM, Menard P, Sand JC, Stucki M, Lukas C, Bartek J, Andersen JS, Lukas J. Larsen DH, et al. J Cell Biol. 2010 Sep 6;190(5):731-40. doi: 10.1083/jcb.200912135. Epub 2010 Aug 30. J Cell Biol. 2010. PMID: 20805324 Free PMC article.
DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy.
Bennetzen MV, Kosar M, Bunkenborg J, Payne MR, Bartkova J, Lindström MS, Lukas J, Andersen JS, Bartek J, Larsen DH. Bennetzen MV, et al. Among authors: larsen dh. Cell Cycle. 2018;17(17):2146-2163. doi: 10.1080/15384101.2018.1515552. Epub 2018 Sep 22. Cell Cycle. 2018. PMID: 30196736 Free PMC article.
Recent advances in the nucleolar responses to DNA double-strand breaks.
Korsholm LM, Gál Z, Nieto B, Quevedo O, Boukoura S, Lund CC, Larsen DH. Korsholm LM, et al. Among authors: larsen dh. Nucleic Acids Res. 2020 Sep 25;48(17):9449-9461. doi: 10.1093/nar/gkaa713. Nucleic Acids Res. 2020. PMID: 32857853 Free PMC article. Review.
39 results