Larkin J - Search Results

1

Isolated imbalance due to bilateral vestibular failure following immune checkpoint inhibitor administration: two cases.

Mendis S, Ealing J, Larkin J, Turajlic S, Carr A, Bronstein A, Kaski D. Mendis S, et al. Among authors: larkin j. Eur J Cancer. 2021 Oct;156:187-189. doi: 10.1016/j.ejca.2021.07.024. Epub 2021 Aug 28. Eur J Cancer. 2021. PMID: 34464870 No abstract available.

2

Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma.

Girotti MR, Pedersen M, Sanchez-Laorden B, Viros A, Turajlic S, Niculescu-Duvaz D, Zambon A, Sinclair J, Hayes A, Gore M, Lorigan P, Springer C, Larkin J, Jorgensen C, Marais R. Girotti MR, et al. Among authors: larkin j. Cancer Discov. 2013 Feb;3(2):158-67. doi: 10.1158/2159-8290.CD-12-0386. Epub 2012 Dec 14. Cancer Discov. 2013. PMID: 23242808 Free PMC article.

3

Targeted therapy and immunotherapy in advanced melanoma: an evolving paradigm.

Khattak M, Fisher R, Turajlic S, Larkin J. Khattak M, et al. Among authors: larkin j. Ther Adv Med Oncol. 2013 Mar;5(2):105-18. doi: 10.1177/1758834012466280. Ther Adv Med Oncol. 2013. PMID: 23450149 Free PMC article.

4

Genome sequencing of mucosal melanomas reveals that they are driven by distinct mechanisms from cutaneous melanoma.

Furney SJ, Turajlic S, Stamp G, Nohadani M, Carlisle A, Thomas JM, Hayes A, Strauss D, Gore M, van den Oord J, Larkin J, Marais R. Furney SJ, et al. Among authors: larkin j. J Pathol. 2013 Jul;230(3):261-9. doi: 10.1002/path.4204. J Pathol. 2013. PMID: 23620124

5

Phase I/II RAF kinase inhibitors in cancer therapy.

Turajlic S, Ali Z, Yousaf N, Larkin J. Turajlic S, et al. Among authors: larkin j. Expert Opin Investig Drugs. 2013 Jun;22(6):739-49. doi: 10.1517/13543784.2013.797964. Epub 2013 May 6. Expert Opin Investig Drugs. 2013. PMID: 23642225 Review.

6

Whole-genome sequencing reveals complex mechanisms of intrinsic resistance to BRAF inhibition.

Turajlic S, Furney SJ, Stamp G, Rana S, Ricken G, Oduko Y, Saturno G, Springer C, Hayes A, Gore M, Larkin J, Marais R. Turajlic S, et al. Among authors: larkin j. Ann Oncol. 2014 May;25(5):959-67. doi: 10.1093/annonc/mdu049. Epub 2014 Feb 6. Ann Oncol. 2014. PMID: 24504448 Free PMC article.

7

BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling.

Sanchez-Laorden B, Viros A, Girotti MR, Pedersen M, Saturno G, Zambon A, Niculescu-Duvaz D, Turajlic S, Hayes A, Gore M, Larkin J, Lorigan P, Cook M, Springer C, Marais R. Sanchez-Laorden B, et al. Among authors: larkin j. Sci Signal. 2014 Mar 25;7(318):ra30. doi: 10.1126/scisignal.2004815. Sci Signal. 2014. PMID: 24667377

8

The mutational burden of acral melanoma revealed by whole-genome sequencing and comparative analysis.

Furney SJ, Turajlic S, Stamp G, Thomas JM, Hayes A, Strauss D, Gavrielides M, Xing W, Gore M, Larkin J, Marais R. Furney SJ, et al. Among authors: larkin j. Pigment Cell Melanoma Res. 2014 Sep;27(5):835-8. doi: 10.1111/pcmr.12279. Epub 2014 Jun 30. Pigment Cell Melanoma Res. 2014. PMID: 24913711

9

PACMEL: a phase 1 dose escalation trial of trametinib (GSK1120212) in combination with paclitaxel.

Coupe N, Corrie P, Hategan M, Larkin J, Gore M, Gupta A, Wise A, Suter S, Ciria C, Love S, Collins L, Middleton MR. Coupe N, et al. Among authors: larkin j. Eur J Cancer. 2015 Feb;51(3):359-66. doi: 10.1016/j.ejca.2014.11.018. Epub 2014 Dec 24. Eur J Cancer. 2015. PMID: 25542057 Clinical Trial.

10

How should clinicians address intratumour heterogeneity in clear cell renal cell carcinoma?

Soultati A, Stares M, Swanton C, Larkin J, Turajlic S. Soultati A, et al. Among authors: larkin j. Curr Opin Urol. 2015 Sep;25(5):358-66. doi: 10.1097/MOU.0000000000000204. Curr Opin Urol. 2015. PMID: 26125509 Review.

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