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Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis.
Craig RA 2nd, Fox BM, Hu C, Lexa KW, Osipov M, Thottumkara AP, Larhammar M, Miyamoto T, Rana A, Kane LA, Yulyaningsih E, Solanoy H, Nguyen H, Chau R, Earr T, Kajiwara Y, Fleck D, Lucas A, Haddick PCG, Takahashi RH, Tong V, Wang J, Canet MJ, Poda SB, Scearce-Levie K, Srivastava A, Sweeney ZK, Xu M, Zhang R, He J, Lei Y, Zhuo Z, de Vicente J. Craig RA 2nd, et al. Among authors: larhammar m. J Med Chem. 2022 Dec 22;65(24):16290-16312. doi: 10.1021/acs.jmedchem.2c01056. Epub 2022 Dec 5. J Med Chem. 2022. PMID: 36469401
Cell Death and Neurodegeneration.
Andreone BJ, Larhammar M, Lewcock JW. Andreone BJ, et al. Among authors: larhammar m. Cold Spring Harb Perspect Biol. 2020 Feb 3;12(2):a036434. doi: 10.1101/cshperspect.a036434. Cold Spring Harb Perspect Biol. 2020. PMID: 31451511 Free PMC article. Review.
Characterization of Dmrt3-Derived Neurons Suggest a Role within Locomotor Circuits.
Perry S, Larhammar M, Vieillard J, Nagaraja C, Hilscher MM, Tafreshiha A, Rofo F, Caixeta FV, Kullander K. Perry S, et al. Among authors: larhammar m. J Neurosci. 2019 Mar 6;39(10):1771-1782. doi: 10.1523/JNEUROSCI.0326-18.2018. Epub 2018 Dec 21. J Neurosci. 2019. PMID: 30578339 Free PMC article.
SLC10A4 is a vesicular amine-associated transporter modulating dopamine homeostasis.
Larhammar M, Patra K, Blunder M, Emilsson L, Peuckert C, Arvidsson E, Rönnlund D, Preobraschenski J, Birgner C, Limbach C, Widengren J, Blom H, Jahn R, Wallén-Mackenzie Å, Kullander K. Larhammar M, et al. Biol Psychiatry. 2015 Mar 15;77(6):526-36. doi: 10.1016/j.biopsych.2014.07.017. Epub 2014 Jul 24. Biol Psychiatry. 2015. PMID: 25176177
14 results