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DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression.
Kong T, Laranjeira ABA, Yang K, Fisher DAC, Yu L, Poittevin De La Frégonnière L, Wang AZ, Ruzinova MB, Fowles JS, Fulbright MC, Cox MJ, Celik H, Challen GA, Huang S, Oh ST. Kong T, et al. Among authors: laranjeira aba. Nat Cancer. 2023 Jan;4(1):108-127. doi: 10.1038/s43018-022-00486-8. Epub 2022 Dec 29. Nat Cancer. 2023. PMID: 36581736
Panobinostat (LBH589) increase survival in adult xenografic model of acute lymphoblastic leukemia with t(4;11) but promotes antagonistic effects in combination with MTX and 6MP.
Moreno DA, Junior HLR, Laranjeira ABA, Cruzeiro GAV, Borges KS, Salomão KB, Ramalho FS, Yunes JA, Silva CLA, Rego EM, Scrideli CA, Tone LG. Moreno DA, et al. Among authors: laranjeira aba. Med Oncol. 2022 Sep 29;39(12):216. doi: 10.1007/s12032-022-01813-w. Med Oncol. 2022. PMID: 36175721
Physiologic IGFBP7 levels prolong IGF1R activation in acute lymphoblastic leukemia.
Artico LL, Laranjeira ABA, Campos LW, Corrêa JR, Zenatti PP, Carvalheira JBC, Brambilla SR, Nowill AE, Brandalise SR, Yunes JA. Artico LL, et al. Among authors: laranjeira aba. Blood Adv. 2021 Sep 28;5(18):3633-3646. doi: 10.1182/bloodadvances.2020003627. Blood Adv. 2021. PMID: 34438446 Free PMC article.
27 results