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A novel tumor suppressor network in squamous malignancies.
Costa C, Santos M, Segrelles C, Dueñas M, Lara MF, Agirre X, Prosper F, García-Escudero R, Paramio JM. Costa C, et al. Among authors: lara mf. Sci Rep. 2012;2:828. doi: 10.1038/srep00828. Epub 2012 Nov 9. Sci Rep. 2012. PMID: 23145321 Free PMC article.
p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia.
Saiz-Ladera C, Lara MF, Garín M, Ruiz S, Santos M, Lorz C, García-Escudero R, Martínez-Fernández M, Bravo A, Fernández-Capetillo O, Segrelles C, Paramio JM. Saiz-Ladera C, et al. Among authors: lara mf. Oncogene. 2014 Sep 11;33(37):4599-4612. doi: 10.1038/onc.2013.417. Epub 2013 Oct 14. Oncogene. 2014. PMID: 24121270 Free PMC article.
p107 acts as a tumor suppressor in pRb-deficient epidermis.
Lara MF, Santos M, Ruiz S, Segrelles C, Moral M, Martínez-Cruz AB, Hernández P, Martínez-Palacio J, Lorz C, García-Escudero R, Paramio JM. Lara MF, et al. Mol Carcinog. 2008 Feb;47(2):105-13. doi: 10.1002/mc.20367. Mol Carcinog. 2008. PMID: 17932945
Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma.
Moral M, Segrelles C, Lara MF, Martínez-Cruz AB, Lorz C, Santos M, García-Escudero R, Lu J, Kiguchi K, Buitrago A, Costa C, Saiz C, Rodriguez-Peralto JL, Martinez-Tello FJ, Rodriguez-Pinilla M, Sanchez-Cespedes M, Garín M, Grande T, Bravo A, DiGiovanni J, Paramio JM. Moral M, et al. Among authors: lara mf. Cancer Res. 2009 Feb 1;69(3):1099-108. doi: 10.1158/0008-5472.CAN-08-3240. Epub 2009 Jan 27. Cancer Res. 2009. PMID: 19176372 Free PMC article.
A functional role of RB-dependent pathway in the control of quiescence in adult epidermal stem cells revealed by genomic profiling.
Lorz C, García-Escudero R, Segrelles C, Garín MI, Ariza JM, Santos M, Ruiz S, Lara MF, Martínez-Cruz AB, Costa C, Buitrago-Pérez A, Saiz-Ladera C, Dueñas M, Paramio JM. Lorz C, et al. Among authors: lara mf. Stem Cell Rev Rep. 2010 Jun;6(2):162-77. doi: 10.1007/s12015-010-9139-0. Stem Cell Rev Rep. 2010. PMID: 20376578 Free PMC article.
Akt mediates an angiogenic switch in transformed keratinocytes.
Segrelles C, Ruiz S, Santos M, Martínez-Palacio J, Lara MF, Paramio JM. Segrelles C, et al. Among authors: lara mf. Carcinogenesis. 2004 Jul;25(7):1137-47. doi: 10.1093/carcin/bgh132. Epub 2004 Mar 4. Carcinogenesis. 2004. PMID: 15001536
40 results