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KLF2 and KLF4 control endothelial identity and vascular integrity.
Sangwung P, Zhou G, Nayak L, Chan ER, Kumar S, Kang DW, Zhang R, Liao X, Lu Y, Sugi K, Fujioka H, Shi H, Lapping SD, Ghosh CC, Higgins SJ, Parikh SM, Jo H, Jain MK. Sangwung P, et al. Among authors: lapping sd. JCI Insight. 2017 Feb 23;2(4):e91700. doi: 10.1172/jci.insight.91700. JCI Insight. 2017. PMID: 28239661 Free PMC article.
Kruppel-like factor 4 regulates neutrophil activation.
Shen Y, Hong H, Sangwung P, Lapping S, Nayak L, Zhang L, Jain MK, Liao X. Shen Y, et al. Among authors: lapping s. Blood Adv. 2017 Apr 20;1(11):662-668. doi: 10.1182/bloodadvances.2017004341. eCollection 2017 Apr 25. Blood Adv. 2017. PMID: 29296708 Free PMC article.
A targetable pathway in neutrophils mitigates both arterial and venous thrombosis.
Nayak L, Sweet DR, Thomas A, Lapping SD, Kalikasingh K, Madera A, Vinayachandran V, Padmanabhan R, Vasudevan NT, Myers JT, Huang AY, Schmaier A, Mackman N, Liao X, Maiseyeu A, Jain MK. Nayak L, et al. Among authors: lapping sd. Sci Transl Med. 2022 Aug 31;14(660):eabj7465. doi: 10.1126/scitranslmed.abj7465. Epub 2022 Aug 31. Sci Transl Med. 2022. PMID: 36044595 Free PMC article.