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Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody.
Baidya M, Chaturvedi M, Dwivedi-Agnihotri H, Ranjan A, Devost D, Namkung Y, Stepniewski TM, Pandey S, Baruah M, Panigrahi B, Sarma P, Yadav MK, Maharana J, Banerjee R, Kawakami K, Inoue A, Selent J, Laporte SA, Hébert TE, Shukla AK. Baidya M, et al. Among authors: laporte sa. Nat Commun. 2022 Aug 8;13(1):4634. doi: 10.1038/s41467-022-32386-x. Nat Commun. 2022. PMID: 35941121 Free PMC article.
Gbetagamma is a negative regulator of AP-1 mediated transcription.
Robitaille M, Gora S, Wang Y, Goupil E, Pétrin D, Del Duca D, Villeneuve LR, Allen BG, Laporte SA, Bernard DJ, Hébert TE. Robitaille M, et al. Among authors: laporte sa. Cell Signal. 2010 Aug;22(8):1254-66. doi: 10.1016/j.cellsig.2010.04.005. Epub 2010 Apr 18. Cell Signal. 2010. PMID: 20403427
A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway.
Goupil E, Tassy D, Bourguet C, Quiniou C, Wisehart V, Pétrin D, Le Gouill C, Devost D, Zingg HH, Bouvier M, Saragovi HU, Chemtob S, Lubell WD, Claing A, Hébert TE, Laporte SA. Goupil E, et al. Among authors: laporte sa. J Biol Chem. 2010 Aug 13;285(33):25624-36. doi: 10.1074/jbc.M110.115196. Epub 2010 Jun 15. J Biol Chem. 2010. PMID: 20551320 Free PMC article.
101 results