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Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance.
Gauttier V, Pengam S, Durand J, Biteau K, Mary C, Morello A, Néel M, Porto G, Teppaz G, Thepenier V, Danger R, Vince N, Wilhelm E, Girault I, Abes R, Ruiz C, Trilleaud C, Ralph K, Trombetta ES, Garcia A, Vignard V, Martinet B, Glémain A, Bruneau S, Haspot F, Dehmani S, Duplouye P, Miyasaka M, Labarrière N, Laplaud D, Le Bas-Bernardet S, Blanquart C, Catros V, Gouraud PA, Archambeaud I, Aublé H, Metairie S, Mosnier JF, Costantini D, Blancho G, Conchon S, Vanhove B, Poirier N. Gauttier V, et al. Among authors: laplaud d. J Clin Invest. 2020 Nov 2;130(11):6109-6123. doi: 10.1172/JCI135528. J Clin Invest. 2020. PMID: 33074246 Free PMC article.
Distribution of Bacterial α1,3-Galactosyltransferase Genes in the Human Gut Microbiome.
Montassier E, Al-Ghalith GA, Mathé C, Le Bastard Q, Douillard V, Garnier A, Guimon R, Raimondeau B, Touchefeu Y, Duchalais E, Vince N, Limou S, Gourraud PA, Laplaud DA, Nicot AB, Soulillou JP, Berthelot L. Montassier E, et al. Front Immunol. 2020 Jan 13;10:3000. doi: 10.3389/fimmu.2019.03000. eCollection 2019. Front Immunol. 2020. PMID: 31998300 Free PMC article.
Patients With Severe Multiple Sclerosis Exhibit Functionally Altered CD8+ Regulatory T Cells.
Benallegue N, Nicol B, Lasselin J, Bézie S, Flippe L, Regue H, Vimond N, Remy S, Garcia A, Le Frère F, Anegon I, Laplaud D, Guillonneau C. Benallegue N, et al. Among authors: laplaud d. Neurol Neuroimmunol Neuroinflamm. 2022 Oct 20;9(6):e200016. doi: 10.1212/NXI.0000000000200016. Print 2022 Nov. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 36266052 Free PMC article.
Expanded CD8 T-cell sharing between periphery and CNS in multiple sclerosis.
Salou M, Garcia A, Michel L, Gainche-Salmon A, Loussouarn D, Nicol B, Guillot F, Hulin P, Nedellec S, Baron D, Ramstein G, Soulillou JP, Brouard S, Nicot AB, Degauque N, Laplaud DA. Salou M, et al. Among authors: laplaud da. Ann Clin Transl Neurol. 2015 Jun;2(6):609-22. doi: 10.1002/acn3.199. Epub 2015 Apr 28. Ann Clin Transl Neurol. 2015. PMID: 26125037 Free PMC article.
Cytotoxic CD8+ T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons.
Coque E, Salsac C, Espinosa-Carrasco G, Varga B, Degauque N, Cadoux M, Crabé R, Virenque A, Soulard C, Fierle JK, Brodovitch A, Libralato M, Végh AG, Venteo S, Scamps F, Boucraut J, Laplaud D, Hernandez J, Gergely C, Vincent T, Raoul C. Coque E, et al. Among authors: laplaud d. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2312-2317. doi: 10.1073/pnas.1815961116. Epub 2019 Jan 23. Proc Natl Acad Sci U S A. 2019. PMID: 30674678 Free PMC article.
Immune Profiling Reveals the T-Cell Effect of Ocrelizumab in Early Relapsing-Remitting Multiple Sclerosis.
Garcia A, Dugast E, Shah S, Morille J, Lebrun-Frenay C, Thouvenot E, De Sèze J, Le Page E, Vukusic S, Maurousset A, Berger E, Casez O, Labauge P, Ruet A, Raposo C, Bakdache F, Buffels R, Le Frère F, Nicot A, Wiertlewski S, Gourraud PA, Berthelot L, Laplaud D. Garcia A, et al. Among authors: laplaud d. Neurol Neuroimmunol Neuroinflamm. 2023 Feb 21;10(3):e200091. doi: 10.1212/NXI.0000000000200091. Print 2023 May. Neurol Neuroimmunol Neuroinflamm. 2023. PMID: 36810163 Free PMC article.
203 results