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The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids.
Stander EA, Lehka B, Carqueijeiro I, Cuello C, Hansson FG, Jansen HJ, Dugé De Bernonville T, Birer Williams C, Vergès V, Lezin E, Lorensen MDBB, Dang TT, Oudin A, Lanoue A, Durand M, Giglioli-Guivarc'h N, Janfelt C, Papon N, Dirks RP, O'connor SE, Jensen MK, Besseau S, Courdavault V. Stander EA, et al. Among authors: lanoue a. Commun Biol. 2023 Nov 24;6(1):1197. doi: 10.1038/s42003-023-05574-8. Commun Biol. 2023. PMID: 38001233 Free PMC article.
A pair of tabersonine 16-hydroxylases initiates the synthesis of vindoline in an organ-dependent manner in Catharanthus roseus.
Besseau S, Kellner F, Lanoue A, Thamm AM, Salim V, Schneider B, Geu-Flores F, Höfer R, Guirimand G, Guihur A, Oudin A, Glevarec G, Foureau E, Papon N, Clastre M, Giglioli-Guivarc'h N, St-Pierre B, Werck-Reichhart D, Burlat V, De Luca V, O'Connor SE, Courdavault V. Besseau S, et al. Among authors: lanoue a. Plant Physiol. 2013 Dec;163(4):1792-803. doi: 10.1104/pp.113.222828. Epub 2013 Oct 9. Plant Physiol. 2013. PMID: 24108213 Free PMC article.
ZCT1 and ZCT2 transcription factors repress the activity of a gene promoter from the methyl erythritol phosphate pathway in Madagascar periwinkle cells.
Chebbi M, Ginis O, Courdavault V, Glévarec G, Lanoue A, Clastre M, Papon N, Gaillard C, Atanassova R, St-Pierre B, Giglioli-Guivarc'h N, Courtois M, Oudin A. Chebbi M, et al. Among authors: lanoue a. J Plant Physiol. 2014 Oct 15;171(16):1510-3. doi: 10.1016/j.jplph.2014.07.004. Epub 2014 Jul 23. J Plant Physiol. 2014. PMID: 25108262
Exploiting Spermidine N-Hydroxycinnamoyltransferase Diversity and Substrate Promiscuity to Produce Various Trihydroxycinnamoyl Spermidines and Analogues in Engineered Yeast.
Perrin J, Kulagina N, Unlubayir M, Munsch T, Carqueijeiro I, Dugé de Bernonville T, De Craene JO, Clastre M, St-Pierre B, Giglioli-Guivarc'h N, Gagneul D, Lanoue A, Courdavault V, Besseau S. Perrin J, et al. Among authors: lanoue a. ACS Synth Biol. 2021 Feb 19;10(2):286-296. doi: 10.1021/acssynbio.0c00391. Epub 2021 Jan 15. ACS Synth Biol. 2021. PMID: 33450150
Enhanced bioproduction of anticancer precursor vindoline by yeast cell factories.
Kulagina N, Guirimand G, Melin C, Lemos-Cruz P, Carqueijeiro I, De Craene JO, Oudin A, Heredia V, Koudounas K, Unlubayir M, Lanoue A, Imbault N, St-Pierre B, Papon N, Clastre M, Giglioli-Guivarc'h N, Marc J, Besseau S, Courdavault V. Kulagina N, et al. Among authors: lanoue a. Microb Biotechnol. 2021 Nov;14(6):2693-2699. doi: 10.1111/1751-7915.13898. Epub 2021 Jul 24. Microb Biotechnol. 2021. PMID: 34302444 Free PMC article.
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