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Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors.
Chimenti F, Bolasco A, Manna F, Secci D, Chimenti P, Granese A, Befani O, Turini P, Cirilli R, La Torre F, Alcaro S, Ortuso F, Langer T. Chimenti F, et al. Among authors: langer t. Curr Med Chem. 2006;13(12):1411-28. doi: 10.2174/092986706776872907. Curr Med Chem. 2006. PMID: 16719786 Review.
Design, synthesis, and SAR analysis of novel selective sigma1 ligands.
Collina S, Loddo G, Urbano M, Linati L, Callegari A, Ortuso F, Alcaro S, Laggner C, Langer T, Prezzavento O, Ronsisvalle G, Azzolina O. Collina S, et al. Among authors: langer t. Bioorg Med Chem. 2007 Jan 15;15(2):771-83. doi: 10.1016/j.bmc.2006.10.048. Epub 2006 Oct 25. Bioorg Med Chem. 2007. PMID: 17088069
Hit finding: towards 'smarter' approaches.
Langer T, Hoffmann R, Bryant S, Lesur B. Langer T, et al. Curr Opin Pharmacol. 2009 Oct;9(5):589-93. doi: 10.1016/j.coph.2009.06.001. Epub 2009 Jul 1. Curr Opin Pharmacol. 2009. PMID: 19576852 Review.
Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.
Chimenti F, Secci D, Bolasco A, Chimenti P, Granese A, Carradori S, Maccioni E, Cardia MC, Yáñez M, Orallo F, Alcaro S, Ortuso F, Cirilli R, Ferretti R, Distinto S, Kirchmair J, Langer T. Chimenti F, et al. Among authors: langer t. Bioorg Med Chem. 2010 Jul 15;18(14):5063-70. doi: 10.1016/j.bmc.2010.05.070. Epub 2010 Jun 1. Bioorg Med Chem. 2010. PMID: 20579890
Cytotoxicity Of Chalcone Of Eugenia aquea Burm F. Leaves Against T47D Breast Cancer Cell Lines And Its Prediction As An Estrogen Receptor Antagonist Based On Pharmacophore-Molecular Dynamics Simulation.
Muchtaridi M, Yusuf M, Syahidah HN, Subarnas A, Zamri A, Bryant SD, Langer T. Muchtaridi M, et al. Among authors: langer t. Adv Appl Bioinform Chem. 2019 Nov 6;12:33-43. doi: 10.2147/AABC.S217205. eCollection 2019. Adv Appl Bioinform Chem. 2019. PMID: 31807030 Free PMC article.
888 results