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A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.
Ramos PS, Criswell LA, Moser KL, Comeau ME, Williams AH, Pajewski NM, Chung SA, Graham RR, Zidovetzki R, Kelly JA, Kaufman KM, Jacob CO, Vyse TJ, Tsao BP, Kimberly RP, Gaffney PM, Alarcón-Riquelme ME, Harley JB, Langefeld CD; International Consortium on the Genetics of Systemic Erythematosus. Ramos PS, et al. Among authors: langefeld cd. PLoS Genet. 2011 Dec;7(12):e1002406. doi: 10.1371/journal.pgen.1002406. Epub 2011 Dec 8. PLoS Genet. 2011. PMID: 22174698 Free PMC article.
Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.
Li JH, Brenner LN, Kaur V, Figueroa K, Schroeder P, Huerta-Chagoya A; MAGIC Investigators; Diabetes Prevention Program (DPP) Research Group; Udler MS, Leong A, Mercader JM, Florez JC. Li JH, et al. Diabetologia. 2023 Jul;66(7):1260-1272. doi: 10.1007/s00125-023-05922-7. Epub 2023 May 26. Diabetologia. 2023. PMID: 37233759 Free PMC article.
Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant.
Wang Q, Martínez-Bonet M, Kim T, Sparks JA, Ishigaki K, Chen X, Sudman M, Aguiar V, Sim S, Hernandez MC, Chiu DJ, Wactor A, Wauford B, Marion MC, Gutierrez-Arcelus M, Bowes J, Eyre S, Nordal E, Prahalad S, Rygg M, Videm V, Raychaudhuri S, Weirauch MT, Langefeld CD, Thompson SD, Nigrovic PA. Wang Q, et al. Among authors: langefeld cd. Cell Genom. 2024 Feb 14;4(2):100502. doi: 10.1016/j.xgen.2024.100502. Cell Genom. 2024. PMID: 38359789 Free PMC article. No abstract available.
A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs.
Venema WJ, Hiddingh S, van Loosdregt J, Bowes J, Balliu B, de Boer JH, Ossewaarde-van Norel J, Thompson SD, Langefeld CD, de Ligt A, van der Veken LT, Krijger PHL, de Laat W, Kuiper JJW. Venema WJ, et al. Among authors: langefeld cd. Cell Genom. 2024 Jan 10;4(1):100460. doi: 10.1016/j.xgen.2023.100460. Epub 2023 Dec 5. Cell Genom. 2024. PMID: 38190099 Free PMC article.
Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.
de Las Fuentes L, Schwander KL, Brown MR, Bentley AR, Winkler TW, Sung YJ, Munroe PB, Miller CL, Aschard H, Aslibekyan S, Bartz TM, Bielak LF, Chai JF, Cheng CY, Dorajoo R, Feitosa MF, Guo X, Hartwig FP, Horimoto A, Kolčić I, Lim E, Liu Y, Manning AK, Marten J, Musani SK, Noordam R, Padmanabhan S, Rankinen T, Richard MA, Ridker PM, Smith AV, Vojinovic D, Zonderman AB, Alver M, Boissel M, Christensen K, Freedman BI, Gao C, Giulianini F, Harris SE, He M, Hsu FC, Kühnel B, Laguzzi F, Li X, Lyytikäinen LP, Nolte IM, Poveda A, Rauramaa R, Riaz M, Robino A, Sofer T, Takeuchi F, Tayo BO, van der Most PJ, Verweij N, Ware EB, Weiss S, Wen W, Yanek LR, Zhan Y, Amin N, Arking DE, Ballantyne C, Boerwinkle E, Brody JA, Broeckel U, Campbell A, Canouil M, Chai X, Chen YI, Chen X, Chitrala KN, Concas MP, de Faire U, de Mutsert R, de Silva HJ, de Vries PS, Do A, Faul JD, Fisher V, Floyd JS, Forrester T, Friedlander Y, Girotto G, Gu CC, Hallmans G, Heikkinen S, Heng CK, Homuth G, Hunt S, Ikram MA, Jacobs DR Jr, Kavousi M, Khor CC, Kilpeläinen TO, Koh WP, Komulainen P, Langefeld CD, Liang J, Liu K, Liu J, Lohman K, Mägi R, Manichaikul AW, McKenzie CA, Meitinger T, Milaneschi Y, Nauck M, Nelso… See abstract for full author list ➔ de Las Fuentes L, et al. Among authors: langefeld cd. Front Genet. 2023 Nov 2;14:1235337. doi: 10.3389/fgene.2023.1235337. eCollection 2023. Front Genet. 2023. PMID: 38028628 Free PMC article.
Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant.
Wang Q, Martínez-Bonet M, Kim T, Sparks JA, Ishigaki K, Chen X, Sudman M, Aguiar V, Sim S, Hernandez MC, Chiu DJ, Wactor A, Wauford B, Marion MC, Gutierrez-Arcelus M, Bowes J, Eyre S, Nordal E, Prahalad S, Rygg M, Videm V, Raychaudhuri S, Weirauch MT, Langefeld CD, Thompson SD, Nigrovic PA. Wang Q, et al. Among authors: langefeld cd. Cell Genom. 2023 Oct 16;3(11):100420. doi: 10.1016/j.xgen.2023.100420. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020975 Free PMC article.
Deep Resequencing of the 1q22 Locus in Non-Lobar Intracerebral Hemorrhage.
Parodi L, Comeau ME, Georgakis MK, Mayerhofer E, Chung J, Falcone GJ, Malik R, Demel SL, Worrall BB, Koch S, Testai FD, Kittner SJ, McCauley JL, Hall CE, Mayson DJ, Elkind MSV, James ML, Woo D, Rosand J, Langefeld CD, Anderson CD. Parodi L, et al. Among authors: langefeld cd. Ann Neurol. 2024 Feb;95(2):325-337. doi: 10.1002/ana.26814. Epub 2023 Oct 14. Ann Neurol. 2024. PMID: 37787451
582 results