Langan P - Search Results

1

Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography.

Wan Q, Parks JM, Hanson BL, Fisher SZ, Ostermann A, Schrader TE, Graham DE, Coates L, Langan P, Kovalevsky A. Wan Q, et al. Among authors: langan p. Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12384-9. doi: 10.1073/pnas.1504986112. Epub 2015 Sep 21. Proc Natl Acad Sci U S A. 2015. PMID: 26392527 Free PMC article.

2

Direct observation of hydrogen atom dynamics and interactions by ultrahigh resolution neutron protein crystallography.

Chen JC, Hanson BL, Fisher SZ, Langan P, Kovalevsky AY. Chen JC, et al. Among authors: langan p. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15301-6. doi: 10.1073/pnas.1208341109. Epub 2012 Sep 4. Proc Natl Acad Sci U S A. 2012. PMID: 22949690 Free PMC article.

3

Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography.

Wan Q, Bennett BC, Wilson MA, Kovalevsky A, Langan P, Howell EE, Dealwis C. Wan Q, et al. Among authors: langan p. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18225-30. doi: 10.1073/pnas.1415856111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. PMID: 25453083 Free PMC article.

4

Heterologous expression, purification, crystallization and preliminary X-ray analysis of Trichoderma reesei xylanase II and four variants.

Wan Q, Kovalevsky A, Zhang Q, Hamilton-Brehm S, Upton R, Weiss KL, Mustyakimov M, Graham D, Coates L, Langan P. Wan Q, et al. Among authors: langan p. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):320-3. doi: 10.1107/S1744309113001164. Epub 2013 Feb 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23519813 Free PMC article.

5

X-ray crystallographic studies of family 11 xylanase Michaelis and product complexes: implications for the catalytic mechanism.

Wan Q, Zhang Q, Hamilton-Brehm S, Weiss K, Mustyakimov M, Coates L, Langan P, Graham D, Kovalevsky A. Wan Q, et al. Among authors: langan p. Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):11-23. doi: 10.1107/S1399004713023626. Epub 2013 Dec 24. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24419374

6

Preliminary joint X-ray and neutron protein crystallographic studies of ecDHFR complexed with folate and NADP+.

Wan Q, Kovalevsky AY, Wilson MA, Bennett BC, Langan P, Dealwis C. Wan Q, et al. Among authors: langan p. Acta Crystallogr F Struct Biol Commun. 2014 Jun;70(Pt 6):814-8. doi: 10.1107/S2053230X1400942X. Epub 2014 May 25. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 24915100 Free PMC article.

7

L-Arabinose binding, isomerization, and epimerization by D-xylose isomerase: X-ray/neutron crystallographic and molecular simulation study.

Langan P, Sangha AK, Wymore T, Parks JM, Yang ZK, Hanson BL, Fisher Z, Mason SA, Blakeley MP, Forsyth VT, Glusker JP, Carrell HL, Smith JC, Keen DA, Graham DE, Kovalevsky A. Langan P, et al. Structure. 2014 Sep 2;22(9):1287-1300. doi: 10.1016/j.str.2014.07.002. Epub 2014 Aug 14. Structure. 2014. PMID: 25132082 Free article.

8

Protein Kinase A Catalytic Subunit Primed for Action: Time-Lapse Crystallography of Michaelis Complex Formation.

Das A, Gerlits O, Parks JM, Langan P, Kovalevsky A, Heller WT. Das A, et al. Among authors: langan p. Structure. 2015 Dec 1;23(12):2331-2340. doi: 10.1016/j.str.2015.10.005. Epub 2015 Nov 12. Structure. 2015. PMID: 26585512 Free article.

9

Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site.

Gerlits O, Wymore T, Das A, Shen CH, Parks JM, Smith JC, Weiss KL, Keen DA, Blakeley MP, Louis JM, Langan P, Weber IT, Kovalevsky A. Gerlits O, et al. Among authors: langan p. Angew Chem Int Ed Engl. 2016 Apr 11;55(16):4924-7. doi: 10.1002/anie.201509989. Epub 2016 Mar 9. Angew Chem Int Ed Engl. 2016. PMID: 26958828 Free PMC article.

10

Visualizing the Bohr effect in hemoglobin: neutron structure of equine cyanomethemoglobin in the R state and comparison with human deoxyhemoglobin in the T state.

Dajnowicz S, Seaver S, Hanson BL, Fisher SZ, Langan P, Kovalevsky AY, Mueser TC. Dajnowicz S, et al. Among authors: langan p. Acta Crystallogr D Struct Biol. 2016 Jul;72(Pt 7):892-903. doi: 10.1107/S2059798316009049. Epub 2016 Jun 28. Acta Crystallogr D Struct Biol. 2016. PMID: 27377386 Free PMC article.

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