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Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease.
Bateman RJ, Smith J, Donohue MC, Delmar P, Abbas R, Salloway S, Wojtowicz J, Blennow K, Bittner T, Black SE, Klein G, Boada M, Grimmer T, Tamaoka A, Perry RJ, Turner RS, Watson D, Woodward M, Thanasopoulou A, Lane C, Baudler M, Fox NC, Cummings JL, Fontoura P, Doody RS; GRADUATE I and II Investigators and the Gantenerumab Study Group. Bateman RJ, et al. Among authors: lane c. N Engl J Med. 2023 Nov 16;389(20):1862-1876. doi: 10.1056/NEJMoa2304430. N Engl J Med. 2023. PMID: 37966285 Clinical Trial.
Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease.
Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, Sperling R, Salloway S, Schofield PR, Masters CL, Martins RN, Rossor MN, Jucker M, Danek A, Förster S, Lane CA, Morris JC, Benzinger TL, Bateman RJ; Dominantly Inherited Alzheimer Network. Wang F, et al. Among authors: lane ca. Neurology. 2015 Sep 1;85(9):790-8. doi: 10.1212/WNL.0000000000001903. Epub 2015 Aug 5. Neurology. 2015. PMID: 26245925 Free PMC article.
Do cerebrospinal fluid transfer methods affect measured amyloid β42, total tau, and phosphorylated tau in clinical practice?
Paterson RW, Toombs J, Chapman MD, Nicholas JM, Heslegrave AJ, Slattery CF, Foulkes AJ, Clark CN, Lane CA, Weston PS, Lunn MP, Fox NC, Zetterberg H, Schott JM. Paterson RW, et al. Among authors: lane ca. Alzheimers Dement (Amst). 2015 Jul 2;1(3):380-4. doi: 10.1016/j.dadm.2015.06.003. eCollection 2015 Sep. Alzheimers Dement (Amst). 2015. PMID: 27239518 Free PMC article.
Alzheimer's disease.
Lane CA, Hardy J, Schott JM. Lane CA, et al. Eur J Neurol. 2018 Jan;25(1):59-70. doi: 10.1111/ene.13439. Epub 2017 Oct 19. Eur J Neurol. 2018. PMID: 28872215 Review.
Hippocampal subfield volumes and pre-clinical Alzheimer's disease in 408 cognitively normal adults born in 1946.
Parker TD, Cash DM, Lane CAS, Lu K, Malone IB, Nicholas JM, James SN, Keshavan A, Murray-Smith H, Wong A, Buchanan SM, Keuss SE, Sudre CH, Modat M, Thomas DL, Crutch SJ, Richards M, Fox NC, Schott JM. Parker TD, et al. Among authors: lane cas. PLoS One. 2019 Oct 17;14(10):e0224030. doi: 10.1371/journal.pone.0224030. eCollection 2019. PLoS One. 2019. PMID: 31622410 Free PMC article.
Associations Between Vascular Risk Across Adulthood and Brain Pathology in Late Life: Evidence From a British Birth Cohort.
Lane CA, Barnes J, Nicholas JM, Sudre CH, Cash DM, Malone IB, Parker TD, Keshavan A, Buchanan SM, Keuss SE, James SN, Lu K, Murray-Smith H, Wong A, Gordon E, Coath W, Modat M, Thomas D, Richards M, Fox NC, Schott JM. Lane CA, et al. JAMA Neurol. 2020 Feb 1;77(2):175-183. doi: 10.1001/jamaneurol.2019.3774. JAMA Neurol. 2020. PMID: 31682678 Free PMC article.
Pure tone audiometry and cerebral pathology in healthy older adults.
Parker T, Cash DM, Lane C, Lu K, Malone IB, Nicholas JM, James S, Keshavan A, Murray-Smith H, Wong A, Buchannan S, Keuss S, Sudre CH, Thomas D, Crutch S, Bamiou DE, Warren JD, Fox NC, Richards M, Schott JM. Parker T, et al. Among authors: lane c. J Neurol Neurosurg Psychiatry. 2020 Feb;91(2):172-176. doi: 10.1136/jnnp-2019-321897. Epub 2019 Nov 7. J Neurol Neurosurg Psychiatry. 2020. PMID: 31699832 Free PMC article.
Olfactory testing does not predict β-amyloid, MRI measures of neurodegeneration or vascular pathology in the British 1946 birth cohort.
Buchanan SM, Parker TD, Lane CA, Keshavan A, Keuss SE, Lu K, James SN, Murray-Smith H, Wong A, Nicholas J, Cash DM, Malone IB, Coath W, Thomas DL, Sudre C, Fox NC, Richards M, Schott JM. Buchanan SM, et al. Among authors: lane ca. J Neurol. 2020 Nov;267(11):3329-3336. doi: 10.1007/s00415-020-10004-4. Epub 2020 Jun 24. J Neurol. 2020. PMID: 32583050 Free PMC article.
Increased variability in reaction time is associated with amyloid beta pathology at age 70.
Lu K, Nicholas JM, James SN, Lane CA, Parker TD, Keshavan A, Keuss SE, Buchanan SM, Murray-Smith H, Cash DM, Sudre CH, Malone IB, Coath W, Wong A, Henley SMD, Fox NC, Richards M, Schott JM, Crutch SJ. Lu K, et al. Among authors: lane ca. Alzheimers Dement (Amst). 2020 Aug 10;12(1):e12076. doi: 10.1002/dad2.12076. eCollection 2020. Alzheimers Dement (Amst). 2020. PMID: 32789161 Free PMC article.
1,271 results