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A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning.
Da Silva O, Probst N, Landry C, Hanak AS, Warnault P, Coisne C, Calas AG, Gosselet F, Courageux C, Gastellier AJ, Trancart M, Baati R, Dehouck MP, Jean L, Nachon F, Renard PY, Dias J. Da Silva O, et al. Among authors: landry c. J Med Chem. 2022 Mar 24;65(6):4649-4666. doi: 10.1021/acs.jmedchem.1c01748. Epub 2022 Mar 7. J Med Chem. 2022. PMID: 35255209 Free PMC article.
Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime.
Calas AG, Hanak AS, Jaffré N, Nervo A, Dias J, Rousseau C, Courageux C, Brazzolotto X, Villa P, Obrecht A, Goossens JF, Landry C, Hachani J, Gosselet F, Dehouck MP, Yerri J, Kliachyna M, Baati R, Nachon F. Calas AG, et al. Among authors: landry c. Biomolecules. 2020 Jun 4;10(6):858. doi: 10.3390/biom10060858. Biomolecules. 2020. PMID: 32512884 Free PMC article.
Chemoselective Hydrogenation of 6-Alkynyl-3-fluoro-2-pyridinaldoximes: Access to First-in-Class 6-Alkyl-3-Fluoro-2-pyridinaldoxime Scaffolds as New Reactivators of Sarin-Inhibited Human Acetylcholinesterase with Increased Blood-Brain Barrier Permeability.
Yerri J, Dias J, Nimmakayala MR, Razafindrainibe F, Courageux C, Gastellier AJ, Jegoux J, Coisne C, Landry C, Gosselet F, Hachani J, Goossens JF, Dehouck MP, Nachon F, Baati R. Yerri J, et al. Among authors: landry c. Chemistry. 2020 Nov 20;26(65):15035-15044. doi: 10.1002/chem.202002012. Epub 2020 Oct 20. Chemistry. 2020. PMID: 32633095
Sodium Transporters Are Involved in Lithium Influx in Brain Endothelial Cells.
Luo H, Gauthier M, Tan X, Landry C, Poupon J, Dehouck MP, Gosselet F, Perrière N, Bellivier F, Cisternino S, Declèves X. Luo H, et al. Among authors: landry c. Mol Pharm. 2018 Jul 2;15(7):2528-2538. doi: 10.1021/acs.molpharmaceut.8b00018. Epub 2018 Jun 14. Mol Pharm. 2018. PMID: 29874916
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain.
Brindisi M, Maramai S, Gemma S, Brogi S, Grillo A, Di Cesare Mannelli L, Gabellieri E, Lamponi S, Saponara S, Gorelli B, Tedesco D, Bonfiglio T, Landry C, Jung KM, Armirotti A, Luongo L, Ligresti A, Piscitelli F, Bertucci C, Dehouck MP, Campiani G, Maione S, Ghelardini C, Pittaluga A, Piomelli D, Di Marzo V, Butini S. Brindisi M, et al. Among authors: landry c. J Med Chem. 2016 Mar 24;59(6):2612-32. doi: 10.1021/acs.jmedchem.5b01812. Epub 2016 Mar 7. J Med Chem. 2016. PMID: 26888301 Free article.
Food-Derived Hemorphins Cross Intestinal and Blood-Brain Barriers In Vitro.
Domenger D, Cudennec B, Kouach M, Touche V, Landry C, Lesage J, Gosselet F, Lestavel S, Goossens JF, Dhulster P, Ravallec R. Domenger D, et al. Among authors: landry c. Front Endocrinol (Lausanne). 2018 Apr 10;9:159. doi: 10.3389/fendo.2018.00159. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 29692758 Free PMC article.
417 results