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Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability.
Ghosh JC, Perego M, Agarwal E, Bertolini I, Wang Y, Goldman AR, Tang HY, Kossenkov AV, Landis CJ, Languino LR, Plow EF, Morotti A, Ottobrini L, Locatelli M, Speicher DW, Caino MC, Cassel J, Salvino JM, Robert ME, Vaira V, Altieri DC. Ghosh JC, et al. Among authors: landis cj. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2115624119. doi: 10.1073/pnas.2115624119. Proc Natl Acad Sci U S A. 2022. PMID: 35177476 Free PMC article.
Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo.
Boyd NH, Walker K, Fried J, Hackney JR, McDonald PC, Benavides GA, Spina R, Audia A, Scott SE, Landis CJ, Tran AN, Bevensee MO, Griguer C, Nozell S, Gillespie GY, Nabors B, Bhat KP, Bar EE, Darley-Usmar V, Xu B, Gordon E, Cooper SJ, Dedhar S, Hjelmeland AB. Boyd NH, et al. Among authors: landis cj. JCI Insight. 2017 Dec 21;2(24):e92928. doi: 10.1172/jci.insight.92928. JCI Insight. 2017. PMID: 29263302 Free PMC article.
Identification of Compounds That Decrease Glioblastoma Growth and Glucose Uptake in Vitro.
Landis CJ, Zhang S, Benavides GA, Scott SE, Li Y, Redmann M, Tran AN, Otamias A, Darley-Usmar V, Napierala M, Zhang J, Augelli-Szafran CE, Zhang W, Hjelmeland AB. Landis CJ, et al. ACS Chem Biol. 2018 Aug 17;13(8):2048-2057. doi: 10.1021/acschembio.8b00251. Epub 2018 Jun 15. ACS Chem Biol. 2018. PMID: 29905460 Free PMC article.