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Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, Hamade H, Murali R, Potdar AA, Wolf AJ, Botwin GJ, Khrom M; International IBD Genetics Consortium; Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Sartor RB, Xavier RJ, Brant SR, Cho JH, Duerr RH, Lazarev MG, Rioux JD, Schumm LP, Silverberg MS, Zaghiyan K, Fleshner P, Melmed GY, Vasiliauskas EA, Ha C, Rabizadeh S, Syal G, Bonthala NN, Ziring DA, Targan SR, Long MD, McGovern DPB, Michelsen KS. Akhlaghpour M, et al. Among authors: landers cj. Gut. 2023 Nov;72(11):2068-2080. doi: 10.1136/gutjnl-2023-329689. Epub 2023 Apr 20. Gut. 2023. PMID: 37080587 Free article.
Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease.
Spivak J, Landers CJ, Vasiliauskas EA, Abreu MT, Dubinsky MC, Papadakis KA, Ippoliti A, Targan SR, Fleshner PR. Spivak J, et al. Among authors: landers cj. Inflamm Bowel Dis. 2006 Dec;12(12):1122-30. doi: 10.1097/01.mib.0000235833.47423.d7. Inflamm Bowel Dis. 2006. PMID: 17119386 Clinical Trial.
TNFRSF1B Is Associated with ANCA in IBD.
Li D, Silverberg MS, Haritunians T, Dubinsky MC, Landers C, Stempak JM, Milgrom R, Guo X, Chen YD, Rotter JI, Taylor KD, McGovern DP, Targan SR. Li D, et al. Inflamm Bowel Dis. 2016 Jun;22(6):1346-52. doi: 10.1097/MIB.0000000000000771. Inflamm Bowel Dis. 2016. PMID: 27104820 Free PMC article.
Serum Analyte Profiles Associated With Crohn's Disease and Disease Location.
Boucher G, Paradis A, Chabot-Roy G, Coderre L, Hillhouse EE, Bitton A, Des Rosiers C, Levings MK, Schumm LP, Lazarev M, Brant SR, Duerr R, McGovern D, Silverberg MS, Cho J, Lesage S, Rioux JD; iGenoMed Consortium; NIDDK IBD Genetics Consortium. Boucher G, et al. Inflamm Bowel Dis. 2022 Jan 5;28(1):9-20. doi: 10.1093/ibd/izab123. Inflamm Bowel Dis. 2022. PMID: 34106269 Free PMC article.
89 results