Lander GC - Search Results

1

Succinylation of a KEAP1 sensor lysine promotes NRF2 activation.

Ibrahim L, Stanton C, Nutsch K, Nguyen T, Li-Ma C, Ko Y, Lander GC, Wiseman RL, Bollong MJ. Ibrahim L, et al. Among authors: lander gc. Cell Chem Biol. 2023 Oct 19;30(10):1295-1302.e4. doi: 10.1016/j.chembiol.2023.07.014. Epub 2023 Aug 23. Cell Chem Biol. 2023. PMID: 37619563

2

The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer.

Chen KC, Qu S, Chowdhury S, Noxon IC, Schonhoft JD, Plate L, Powers ET, Kelly JW, Lander GC, Wiseman RL. Chen KC, et al. Among authors: lander gc. EMBO J. 2017 Aug 1;36(15):2296-2309. doi: 10.15252/embj.201695616. Epub 2017 Jun 27. EMBO J. 2017. PMID: 28655754 Free PMC article.

3

Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing.

Puchades C, Rampello AJ, Shin M, Giuliano CJ, Wiseman RL, Glynn SE, Lander GC. Puchades C, et al. Among authors: lander gc. Science. 2017 Nov 3;358(6363):eaao0464. doi: 10.1126/science.aao0464. Science. 2017. PMID: 29097521 Free PMC article.

4

Unique Structural Features of the Mitochondrial AAA+ Protease AFG3L2 Reveal the Molecular Basis for Activity in Health and Disease.

Puchades C, Ding B, Song A, Wiseman RL, Lander GC, Glynn SE. Puchades C, et al. Among authors: lander gc. Mol Cell. 2019 Sep 5;75(5):1073-1085.e6. doi: 10.1016/j.molcel.2019.06.016. Epub 2019 Jul 18. Mol Cell. 2019. PMID: 31327635 Free PMC article.

5

Structural basis for distinct operational modes and protease activation in AAA+ protease Lon.

Shin M, Puchades C, Asmita A, Puri N, Adjei E, Wiseman RL, Karzai AW, Lander GC. Shin M, et al. Among authors: lander gc. Sci Adv. 2020 May 20;6(21):eaba8404. doi: 10.1126/sciadv.aba8404. eCollection 2020 May. Sci Adv. 2020. PMID: 32490208 Free PMC article.

6

Structures of the human LONP1 protease reveal regulatory steps involved in protease activation.

Shin M, Watson ER, Song AS, Mindrebo JT, Novick SJ, Griffin PR, Wiseman RL, Lander GC. Shin M, et al. Among authors: lander gc. Nat Commun. 2021 May 28;12(1):3239. doi: 10.1038/s41467-021-23495-0. Nat Commun. 2021. PMID: 34050165 Free PMC article.

7

Cryo-EM structure of hexameric yeast Lon protease (PIM1) highlights the importance of conserved structural elements.

Yang J, Song AS, Wiseman RL, Lander GC. Yang J, et al. Among authors: lander gc. J Biol Chem. 2022 Mar;298(3):101694. doi: 10.1016/j.jbc.2022.101694. Epub 2022 Feb 7. J Biol Chem. 2022. PMID: 35143841 Free PMC article.

8

Succinylation of a KEAP1 sensor lysine promotes NRF2 activation.

Ibrahim L, Stanton C, Nutsch K, Nguyen T, Li-Ma C, Ko Y, Lander GC, Wiseman RL, Bollong MJ. Ibrahim L, et al. Among authors: lander gc. bioRxiv [Preprint]. 2023 May 9:2023.05.08.539908. doi: 10.1101/2023.05.08.539908. bioRxiv. 2023. PMID: 37215033 Free PMC article. Updated. Preprint.

9

The molecular principles governing the activity and functional diversity of AAA+ proteins.

Puchades C, Sandate CR, Lander GC. Puchades C, et al. Among authors: lander gc. Nat Rev Mol Cell Biol. 2020 Jan;21(1):43-58. doi: 10.1038/s41580-019-0183-6. Epub 2019 Nov 21. Nat Rev Mol Cell Biol. 2020. PMID: 31754261 Free PMC article. Review.

10

DELE1 oligomerization promotes integrated stress response activation.

Yang J, Baron KR, Pride DE, Schneemann A, Guo X, Chen W, Song AS, Aviles G, Kampmann M, Wiseman RL, Lander GC. Yang J, et al. Among authors: lander gc. Nat Struct Mol Biol. 2023 Sep;30(9):1295-1302. doi: 10.1038/s41594-023-01061-0. Epub 2023 Aug 7. Nat Struct Mol Biol. 2023. PMID: 37550454 Free PMC article.

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