Lander GC - Search Results

1

A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.

Matyskiela ME, Lu G, Ito T, Pagarigan B, Lu CC, Miller K, Fang W, Wang NY, Nguyen D, Houston J, Carmel G, Tran T, Riley M, Nosaka L, Lander GC, Gaidarova S, Xu S, Ruchelman AL, Handa H, Carmichael J, Daniel TO, Cathers BE, Lopez-Girona A, Chamberlain PP. Matyskiela ME, et al. Among authors: lander gc. Nature. 2016 Jul 14;535(7611):252-7. doi: 10.1038/nature18611. Epub 2016 Jun 22. Nature. 2016. PMID: 27338790

2

Complete subunit architecture of the proteasome regulatory particle.

Lander GC, Estrin E, Matyskiela ME, Bashore C, Nogales E, Martin A. Lander GC, et al. Nature. 2012 Jan 11;482(7384):186-91. doi: 10.1038/nature10774. Nature. 2012. PMID: 22237024 Free PMC article.

3

Conformational switching of the 26S proteasome enables substrate degradation.

Matyskiela ME, Lander GC, Martin A. Matyskiela ME, et al. Among authors: lander gc. Nat Struct Mol Biol. 2013 Jul;20(7):781-8. doi: 10.1038/nsmb.2616. Epub 2013 Jun 16. Nat Struct Mol Biol. 2013. PMID: 23770819 Free PMC article.

4

Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome.

Bashore C, Dambacher CM, Goodall EA, Matyskiela ME, Lander GC, Martin A. Bashore C, et al. Among authors: lander gc. Nat Struct Mol Biol. 2015 Sep;22(9):712-9. doi: 10.1038/nsmb.3075. Epub 2015 Aug 24. Nat Struct Mol Biol. 2015. PMID: 26301997 Free PMC article.

5

Thermodynamic Interrogation of the Assembly of a Viral Genome Packaging Motor Complex.

Yang TC, Ortiz D, Nosaka L, Lander GC, Catalano CE. Yang TC, et al. Among authors: lander gc. Biophys J. 2015 Oct 20;109(8):1663-75. doi: 10.1016/j.bpj.2015.08.037. Biophys J. 2015. PMID: 26488657 Free PMC article.

6

Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation.

Greene ER, Goodall EA, de la Peña AH, Matyskiela ME, Lander GC, Martin A. Greene ER, et al. Among authors: lander gc. Elife. 2019 Nov 28;8:e49806. doi: 10.7554/eLife.49806. Elife. 2019. PMID: 31778111 Free PMC article.

7

Molecular glue CELMoD compounds are regulators of cereblon conformation.

Watson ER, Novick S, Matyskiela ME, Chamberlain PP, H de la Peña A, Zhu J, Tran E, Griffin PR, Wertz IE, Lander GC. Watson ER, et al. Among authors: lander gc. Science. 2022 Nov 4;378(6619):549-553. doi: 10.1126/science.add7574. Epub 2022 Nov 3. Science. 2022. PMID: 36378961 Free PMC article.

8

Exploring icosahedral virus structures with VIPER.

Natarajan P, Lander GC, Shepherd CM, Reddy VS, Brooks CL 3rd, Johnson JE. Natarajan P, et al. Among authors: lander gc. Nat Rev Microbiol. 2005 Oct;3(10):809-17. doi: 10.1038/nrmicro1283. Nat Rev Microbiol. 2005. PMID: 16205712 Review.

9

Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex.

Chowdhury S, Carter J, Rollins MF, Golden SM, Jackson RN, Hoffmann C, Nosaka L, Bondy-Denomy J, Maxwell KL, Davidson AR, Fischer ER, Lander GC, Wiedenheft B. Chowdhury S, et al. Among authors: lander gc. Cell. 2017 Mar 23;169(1):47-57.e11. doi: 10.1016/j.cell.2017.03.012. Cell. 2017. PMID: 28340349 Free PMC article.

10

Achieving better-than-3-Å resolution by single-particle cryo-EM at 200 keV.

Herzik MA Jr, Wu M, Lander GC. Herzik MA Jr, et al. Among authors: lander gc. Nat Methods. 2017 Nov;14(11):1075-1078. doi: 10.1038/nmeth.4461. Epub 2017 Oct 9. Nat Methods. 2017. PMID: 28991891 Free PMC article.

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