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SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia.
Leukemia. 2021 Feb;35(2):377-388. doi: 10.1038/s41375-020-0845-6. Epub 2020 May 7.
Leukemia. 2021.
PMID: 32382081
Free PMC article.
A novel and highly effective mitochondrial uncoupling drug in T-cell leukemia.
da Silva-Diz V, Cao B, Lancho O, Chiles E, Alasadi A, Aleksandrova M, Luo S, Singh A, Tao H, Augeri D, Minuzzo S, Indraccolo S, Khiabanian H, Su X, Jin S, Herranz D.
da Silva-Diz V, et al. Among authors: lancho o.
Blood. 2021 Oct 14;138(15):1317-1330. doi: 10.1182/blood.2020008955.
Blood. 2021.
PMID: 33876224
Free PMC article.
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The MYC Enhancer-ome: Long-Range Transcriptional Regulation of MYC in Cancer.
Lancho O, Herranz D.
Lancho O, et al.
Trends Cancer. 2018 Dec;4(12):810-822. doi: 10.1016/j.trecan.2018.10.003. Epub 2018 Nov 2.
Trends Cancer. 2018.
PMID: 30470303
Free PMC article.
Review.
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A Tumor Suppressor Enhancer of PTEN in T-cell development and leukemia.
Tottone L, Lancho O, Loh JW, Singh A, Kimura S, Roels J, Kuchmiy A, Strubbe S, Lawlor MA, da Silva-Diz V, Luo S, Gachet S, García-Prieto CA, Hagelaar R, Esteller M, Meijerink JPP, Soulier J, Taghon T, Van Vlierberghe P, Mullighan CG, Khiabanian H, Rocha PP, Herranz D.
Tottone L, et al. Among authors: lancho o.
Blood Cancer Discov. 2021 Jan;2(1):92-109. doi: 10.1158/2643-3230.BCD-20-0201. Epub 2020 Nov 24.
Blood Cancer Discov. 2021.
PMID: 33458694
Free PMC article.
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Therapeutic targeting of ACLY in T-ALL in vivo.
da Silva-Diz V, Singh A, Lancho O, Aleksandrova M, Mandleywala K, Nunes PR, Khatun J, Kim O, Chiles E, Su X, Khiabanian H, Wellen KE, Herranz D.
da Silva-Diz V, et al. Among authors: lancho o.
bioRxiv [Preprint]. 2023 Mar 28:2023.03.27.534395. doi: 10.1101/2023.03.27.534395.
bioRxiv. 2023.
PMID: 37034581
Free PMC article.
Preprint.
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A Therapeutically Targetable NOTCH1-SIRT1-KAT7 Axis in T-cell Leukemia.
Lancho O, Singh A, da Silva-Diz V, Aleksandrova M, Khatun J, Tottone L, Nunes PR, Luo S, Zhao C, Zheng H, Chiles E, Zuo Z, Rocha PP, Su X, Khiabanian H, Herranz D.
Lancho O, et al.
Blood Cancer Discov. 2023 Jan 6;4(1):12-33. doi: 10.1158/2643-3230.BCD-22-0098.
Blood Cancer Discov. 2023.
PMID: 36322781
Free PMC article.
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