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Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance.
Lan T, Ganapathy US, Sharma S, Ahn YM, Zimmerman M, Molodtsov V, Hegde P, Gengenbacher M, Ebright RH, Dartois V, Freundlich JS, Dick T, Aldrich CC. Lan T, et al. Angew Chem Int Ed Engl. 2022 Nov 7;61(45):e202211498. doi: 10.1002/anie.202211498. Epub 2022 Oct 12. Angew Chem Int Ed Engl. 2022. PMID: 36222275 Free PMC article.
Blocking Bacterial Naphthohydroquinone Oxidation and ADP-Ribosylation Improves Activity of Rifamycins against Mycobacterium abscessus.
Ganapathy US, Lan T, Krastel P, Lindman M, Zimmerman MD, Ho H, Sarathy JP, Evans JC, Dartois V, Aldrich CC, Dick T. Ganapathy US, et al. Among authors: lan t. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0097821. doi: 10.1128/AAC.00978-21. Epub 2021 Aug 17. Antimicrob Agents Chemother. 2021. PMID: 34228543 Free PMC article.
Amycolatopsis mediterranei: A Sixty-Year Journey from Strain Isolation to Unlocking Its Potential of Rifamycin Analogue Production by Combinatorial Biosynthesis.
Sood U, Müller M, Lan T, Garg G, Singhvi N, Hira P, Singh P, Nigam A, Verma M, Lata P, Kaur H, Kumar A, Rawat CD, Lal S, Aldrich C, Bechthold A, Lal R. Sood U, et al. Among authors: lan t. J Nat Prod. 2024 Feb 23;87(2):424-438. doi: 10.1021/acs.jnatprod.3c00686. Epub 2024 Jan 30. J Nat Prod. 2024. PMID: 38289177 Review.
Angiocrine signaling in sinusoidal homeostasis and liver diseases.
Gao J, Lan T, Kostallari E, Guo Y, Lai E, Guillot A, Ding B, Tacke F, Tang C, Shah VH. Gao J, et al. Among authors: lan t. J Hepatol. 2024 May 17:S0168-8278(24)00349-0. doi: 10.1016/j.jhep.2024.05.014. Online ahead of print. J Hepatol. 2024. PMID: 38763358 Review.
1,827 results