Lan K - Search Results

1

Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism.

Zheng X, Chen T, Jiang R, Zhao A, Wu Q, Kuang J, Sun D, Ren Z, Li M, Zhao M, Wang S, Bao Y, Li H, Hu C, Dong B, Li D, Wu J, Xia J, Wang X, Lan K, Rajani C, Xie G, Lu A, Jia W, Jiang C, Jia W. Zheng X, et al. Among authors: lan k. Cell Metab. 2021 Apr 6;33(4):791-803.e7. doi: 10.1016/j.cmet.2020.11.017. Epub 2020 Dec 17. Cell Metab. 2021. PMID: 33338411 Free article.

2

An integrated metabolomics and pharmacokinetics strategy for multi-component drugs evaluation.

Lan K, Jia W. Lan K, et al. Curr Drug Metab. 2010 Jan;11(1):105-14. doi: 10.2174/138920010791110926. Curr Drug Metab. 2010. PMID: 20302568 Review.

3

Metabolic fate of tea polyphenols in humans.

Xie G, Zhao A, Zhao L, Chen T, Chen H, Qi X, Zheng X, Ni Y, Cheng Y, Lan K, Yao C, Qiu M, Jia W. Xie G, et al. Among authors: lan k. J Proteome Res. 2012 Jun 1;11(6):3449-57. doi: 10.1021/pr300318m. Epub 2012 May 17. J Proteome Res. 2012. PMID: 22559253

4

Towards polypharmacokinetics: pharmacokinetics of multicomponent drugs and herbal medicines using a metabolomics approach.

Lan K, Xie G, Jia W. Lan K, et al. Evid Based Complement Alternat Med. 2013;2013:819147. doi: 10.1155/2013/819147. Epub 2013 Mar 14. Evid Based Complement Alternat Med. 2013. PMID: 23573155 Free PMC article.

5

Key Role for the 12-Hydroxy Group in the Negative Ion Fragmentation of Unconjugated C24 Bile Acids.

Lan K, Su M, Xie G, Ferslew BC, Brouwer KL, Rajani C, Liu C, Jia W. Lan K, et al. Anal Chem. 2016 Jul 19;88(14):7041-8. doi: 10.1021/acs.analchem.6b00573. Epub 2016 Jun 30. Anal Chem. 2016. PMID: 27322813 Free PMC article.

6

Poly-pharmacokinetic Study of a Multicomponent Herbal Medicine in Healthy Chinese Volunteers.

Xie G, Wang S, Zhang H, Zhao A, Liu J, Ma Y, Lan K, Ni Y, Liu C, Liu P, Chen T, Jia W. Xie G, et al. Among authors: lan k. Clin Pharmacol Ther. 2018 Apr;103(4):692-702. doi: 10.1002/cpt.784. Epub 2017 Sep 19. Clin Pharmacol Ther. 2018. PMID: 28675423

7

Factors affecting separation and detection of bile acids by liquid chromatography coupled with mass spectrometry in negative mode.

Yin S, Su M, Xie G, Li X, Wei R, Liu C, Lan K, Jia W. Yin S, et al. Among authors: lan k. Anal Bioanal Chem. 2017 Sep;409(23):5533-5545. doi: 10.1007/s00216-017-0489-1. Epub 2017 Jul 8. Anal Bioanal Chem. 2017. PMID: 28689325 Free PMC article.

8

Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids.

Zhu P, Zhang J, Chen Y, Yin S, Su M, Xie G, Brouwer KLR, Liu C, Lan K, Jia W. Zhu P, et al. Among authors: lan k. Anal Bioanal Chem. 2018 Aug;410(21):5287-5300. doi: 10.1007/s00216-018-1183-7. Epub 2018 Jun 16. Anal Bioanal Chem. 2018. PMID: 29907951 Free PMC article.

9

Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species.

Zhang J, Gao LZ, Chen YJ, Zhu PP, Yin SS, Su MM, Ni Y, Miao J, Wu WL, Chen H, Brouwer KLR, Liu CX, Xu L, Jia W, Lan K. Zhang J, et al. Among authors: lan k. Drug Metab Dispos. 2019 Mar;47(3):283-294. doi: 10.1124/dmd.118.085670. Epub 2019 Jan 3. Drug Metab Dispos. 2019. PMID: 30606729 Free PMC article. Clinical Trial.

10

Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deoxycholate 19-Hydroxylation Is an In Vitro Marker of CYP3A7 Activity.

Chen YJ, Zhang J, Zhu PP, Tan XW, Lin QH, Wang WX, Yin SS, Gao LZ, Su MM, Liu CX, Xu L, Jia W, Sevrioukova IF, Lan K. Chen YJ, et al. Among authors: lan k. Drug Metab Dispos. 2019 Jun;47(6):574-581. doi: 10.1124/dmd.119.086637. Epub 2019 Mar 27. Drug Metab Dispos. 2019. PMID: 30918015 Free PMC article.

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