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Genetic loci linked to type 1 diabetes and multiple sclerosis families in Sardinia.
Pitzalis M, Zavattari P, Murru R, Deidda E, Zoledziewska M, Murru D, Moi L, Motzo C, Orrù V, Costa G, Solla E, Fadda E, Schirru L, Melis MC, Lai M, Mancosu C, Tranquilli S, Cuccu S, Rolesu M, Secci MA, Corongiu D, Contu D, Lampis R, Nucaro A, Pala G, Pacifico A, Maioli M, Frongia P, Chessa M, Ricciardi R, Lostia S, Marinaro AM, Milia AF, Landis N, Zedda MA, Whalen MB, Santoni F, Marrosu MG, Devoto M, Cucca F. Pitzalis M, et al. Among authors: lampis r. BMC Med Genet. 2008 Jan 20;9:3. doi: 10.1186/1471-2350-9-3. BMC Med Genet. 2008. PMID: 18205952 Free PMC article.
Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DQB1, -DRB1 disease loci.
Zavattari P, Lampis R, Motzo C, Loddo M, Mulargia A, Whalen M, Maioli M, Angius E, Todd JA, Cucca F. Zavattari P, et al. Among authors: lampis r. Hum Mol Genet. 2001 Apr 1;10(8):881-9. doi: 10.1093/hmg/10.8.881. Hum Mol Genet. 2001. PMID: 11285254
Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in Sardinia.
Zoledziewska M, Costa G, Pitzalis M, Cocco E, Melis C, Moi L, Zavattari P, Murru R, Lampis R, Morelli L, Poddie F, Frongia P, Pusceddu P, Bajorek M, Marras A, Satta AM, Chessa A, Pugliatti M, Sotgiu S, Whalen MB, Rosati G, Cucca F, Marrosu MG. Zoledziewska M, et al. Among authors: lampis r. Genes Immun. 2009 Jan;10(1):15-7. doi: 10.1038/gene.2008.84. Epub 2008 Oct 23. Genes Immun. 2009. PMID: 18946483
40 results