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Cancer vulnerabilities unveiled by genomic loss.
Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC. Nijhawan D, et al. Among authors: lamothe r. Cell. 2012 Aug 17;150(4):842-54. doi: 10.1016/j.cell.2012.07.023. Cell. 2012. PMID: 22901813 Free PMC article.
Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability.
Paolella BR, Gibson WJ, Urbanski LM, Alberta JA, Zack TI, Bandopadhayay P, Nichols CA, Agarwalla PK, Brown MS, Lamothe R, Yu Y, Choi PS, Obeng EA, Heckl D, Wei G, Wang B, Tsherniak A, Vazquez F, Weir BA, Root DE, Cowley GS, Buhrlage SJ, Stiles CD, Ebert BL, Hahn WC, Reed R, Beroukhim R. Paolella BR, et al. Among authors: lamothe r. Elife. 2017 Feb 8;6:e23268. doi: 10.7554/eLife.23268. Elife. 2017. PMID: 28177281 Free PMC article.
Cohesin residency determines chromatin loop patterns.
Costantino L, Hsieh TS, Lamothe R, Darzacq X, Koshland D. Costantino L, et al. Among authors: lamothe r. Elife. 2020 Nov 10;9:e59889. doi: 10.7554/eLife.59889. Elife. 2020. PMID: 33170773 Free PMC article.
An Arabidopsis gene regulatory network for secondary cell wall synthesis.
Taylor-Teeples M, Lin L, de Lucas M, Turco G, Toal TW, Gaudinier A, Young NF, Trabucco GM, Veling MT, Lamothe R, Handakumbura PP, Xiong G, Wang C, Corwin J, Tsoukalas A, Zhang L, Ware D, Pauly M, Kliebenstein DJ, Dehesh K, Tagkopoulos I, Breton G, Pruneda-Paz JL, Ahnert SE, Kay SA, Hazen SP, Brady SM. Taylor-Teeples M, et al. Among authors: lamothe r. Nature. 2015 Jan 29;517(7536):571-5. doi: 10.1038/nature14099. Epub 2014 Dec 24. Nature. 2015. PMID: 25533953 Free PMC article.
Rational design of a SOCS1-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens.
Schlabach MR, Lin S, Collester ZR, Wrocklage C, Shenker S, Calnan C, Xu T, Gannon HS, Williams LJ, Thompson F, Dunbar PR, LaMothe RA, Garrett TE, Colletti N, Hohmann AF, Tubo NJ, Bullock CP, Le Mercier I, Sofjan K, Merkin JJ, Keegan S, Kryukov GV, Dugopolski C, Stegmeier F, Wong K, Sharp FA, Cadzow L, Benson MJ. Schlabach MR, et al. Among authors: lamothe ra. J Clin Invest. 2023 Dec 15;133(24):e163096. doi: 10.1172/JCI163096. J Clin Invest. 2023. PMID: 38099496 Free PMC article.
Detecting Anosognosia from the Prodromal Stage of Alzheimer's Disease.
Guieysse T, Lamothe R, Houot M, Razafimahatratra S, Medani T, Lejeune FX, Dreyfus G, Klarsfeld A, Pantazis D, Koechlin E, Andrade K. Guieysse T, et al. Among authors: lamothe r. J Alzheimers Dis. 2023;95(4):1723-1733. doi: 10.3233/JAD-230552. J Alzheimers Dis. 2023. PMID: 37718816 Free PMC article.
Novel and Engineered Type II CRISPR Systems from Uncultivated Microbes with Broad Genome Editing Capability.
Alexander LM, Aliaga Goltsman DS, Liu J, Lin JL, Temoche-Diaz MM, Laperriere SM, Neerincx A, Bednarski C, Knyphausen P, Cohnen A, Albers J, Gonzalez-Osorio L, Fregoso Ocampo R, Oki J, Devoto AE, Castelle CJ, Lamothe RC, Cost GJ, Butterfield CN, Thomas BC, Brown CT. Alexander LM, et al. Among authors: lamothe rc. CRISPR J. 2023 Jun;6(3):261-277. doi: 10.1089/crispr.2022.0090. CRISPR J. 2023. PMID: 37272861 Free PMC article.
50 results