Lamore SD - Search Results

1

An impedance-based cellular assay using human iPSC-derived cardiomyocytes to quantify modulators of cardiac contractility.

Scott CW, Zhang X, Abi-Gerges N, Lamore SD, Abassi YA, Peters MF. Scott CW, et al. Among authors: lamore sd. Toxicol Sci. 2014 Dec;142(2):331-8. doi: 10.1093/toxsci/kfu186. Epub 2014 Sep 18. Toxicol Sci. 2014. PMID: 25237062

2

Cellular impedance assays for predictive preclinical drug screening of kinase inhibitor cardiovascular toxicity.

Lamore SD, Kamendi HW, Scott CW, Dragan YP, Peters MF. Lamore SD, et al. Toxicol Sci. 2013 Oct;135(2):402-13. doi: 10.1093/toxsci/kft167. Epub 2013 Jul 28. Toxicol Sci. 2013. PMID: 23897988

3

Human stem cell-derived cardiomyocytes in cellular impedance assays: bringing cardiotoxicity screening to the front line.

Peters MF, Lamore SD, Guo L, Scott CW, Kolaja KL. Peters MF, et al. Among authors: lamore sd. Cardiovasc Toxicol. 2015 Apr;15(2):127-39. doi: 10.1007/s12012-014-9268-9. Cardiovasc Toxicol. 2015. PMID: 25134468 Review.

4

Deconvoluting Kinase Inhibitor Induced Cardiotoxicity.

Lamore SD, Ahlberg E, Boyer S, Lamb ML, Hortigon-Vinagre MP, Rodriguez V, Smith GL, Sagemark J, Carlsson L, Bates SM, Choy AL, Stålring J, Scott CW, Peters MF. Lamore SD, et al. Toxicol Sci. 2017 Jul 1;158(1):213-226. doi: 10.1093/toxsci/kfx082. Toxicol Sci. 2017. PMID: 28453775 Free PMC article.

5

Cardiovascular Toxicity Induced by Kinase Inhibitors: Mechanisms and Preclinical Approaches.

Lamore SD, Kohnken RA, Peters MF, Kolaja KL. Lamore SD, et al. Chem Res Toxicol. 2020 Jan 21;33(1):125-136. doi: 10.1021/acs.chemrestox.9b00387. Epub 2020 Jan 10. Chem Res Toxicol. 2020. PMID: 31840498 Review.

6

Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo.

Halkina T, Henderson JL, Lin EY, Himmelbauer MK, Jones JH, Nevalainen M, Feng J, King K, Rooney M, Johnson JL, Marcotte DJ, Chodaparambil JV, Kumar PR, Patterson TA, Murugan P, Schuman E, Wong L, Hesson T, Lamore S, Bao C, Calhoun M, Certo H, Amaral B, Dillon GM, Gilfillan R, de Turiso FG. Halkina T, et al. J Med Chem. 2021 May 13;64(9):6358-6380. doi: 10.1021/acs.jmedchem.1c00382. Epub 2021 May 4. J Med Chem. 2021. PMID: 33944571

7

The malondialdehyde-derived fluorophore DHP-lysine is a potent sensitizer of UVA-induced photooxidative stress in human skin cells.

Lamore SD, Azimian S, Horn D, Anglin BL, Uchida K, Cabello CM, Wondrak GT. Lamore SD, et al. J Photochem Photobiol B. 2010 Dec 2;101(3):251-64. doi: 10.1016/j.jphotobiol.2010.07.010. Epub 2010 Jul 30. J Photochem Photobiol B. 2010. PMID: 20724175 Free PMC article.

8

Autophagic-lysosomal dysregulation downstream of cathepsin B inactivation in human skin fibroblasts exposed to UVA.

Lamore SD, Wondrak GT. Lamore SD, et al. Photochem Photobiol Sci. 2012 Jan;11(1):163-72. doi: 10.1039/c1pp05131h. Epub 2011 Jul 20. Photochem Photobiol Sci. 2012. PMID: 21773629 Free PMC article.

9

HMGB1-directed drug discovery targeting cutaneous inflammatory dysregulation.

Lamore SD, Cabello CM, Wondrak GT. Lamore SD, et al. Curr Drug Metab. 2010 Mar;11(3):250-65. doi: 10.2174/138920010791196337. Curr Drug Metab. 2010. PMID: 20406187 Review.

10

The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A(p21) upregulation in human cancer cell lines.

Cabello CM, Bair WB 3rd, Ley S, Lamore SD, Azimian S, Wondrak GT. Cabello CM, et al. Among authors: lamore sd. Biochem Pharmacol. 2009 Apr 1;77(7):1125-38. doi: 10.1016/j.bcp.2008.12.002. Epub 2008 Dec 24. Biochem Pharmacol. 2009. PMID: 19186174 Free PMC article.

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