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Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice.
Pak HH, Haws SA, Green CL, Koller M, Lavarias MT, Richardson NE, Yang SE, Dumas SN, Sonsalla M, Bray L, Johnson M, Barnes S, Darley-Usmar V, Zhang J, Yen CE, Denu JM, Lamming DW. Pak HH, et al. Among authors: lamming dw. Nat Metab. 2021 Oct;3(10):1327-1341. doi: 10.1038/s42255-021-00466-9. Epub 2021 Oct 18. Nat Metab. 2021. PMID: 34663973 Free PMC article.
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Yilmaz ÖH, Katajisto P, Lamming DW, Gültekin Y, Bauer-Rowe KE, Sengupta S, Birsoy K, Dursun A, Yilmaz VO, Selig M, Nielsen GP, Mino-Kenudson M, Zukerberg LR, Bhan AK, Deshpande V, Sabatini DM. Yilmaz ÖH, et al. Among authors: lamming dw. Nature. 2012 Jun 28;486(7404):490-5. doi: 10.1038/nature11163. Nature. 2012. PMID: 22722868 Free PMC article.
Restoration of metabolic health by decreased consumption of branched-chain amino acids.
Cummings NE, Williams EM, Kasza I, Konon EN, Schaid MD, Schmidt BA, Poudel C, Sherman DS, Yu D, Arriola Apelo SI, Cottrell SE, Geiger G, Barnes ME, Wisinski JA, Fenske RJ, Matkowskyj KA, Kimple ME, Alexander CM, Merrins MJ, Lamming DW. Cummings NE, et al. Among authors: lamming dw. J Physiol. 2018 Feb 15;596(4):623-645. doi: 10.1113/JP275075. Epub 2017 Dec 27. J Physiol. 2018. PMID: 29266268 Free PMC article.
109 results