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Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport.
Nat Struct Mol Biol. 2023 Sep;30(9):1365-1379. doi: 10.1038/s41594-023-01010-x. Epub 2023 Jun 15.
Nat Struct Mol Biol. 2023.
PMID: 37322240
Free PMC article.
The dynein cortical anchor Num1 activates dynein motility by relieving Pac1/LIS1-mediated inhibition.
Lammers LG, Markus SM.
Lammers LG, et al.
J Cell Biol. 2015 Oct 26;211(2):309-22. doi: 10.1083/jcb.201506119. Epub 2015 Oct 19.
J Cell Biol. 2015.
PMID: 26483554
Free PMC article.
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She1 affects dynein through direct interactions with the microtubule and the dynein microtubule-binding domain.
Ecklund KH, Morisaki T, Lammers LG, Marzo MG, Stasevich TJ, Markus SM.
Ecklund KH, et al. Among authors: lammers lg.
Nat Commun. 2017 Dec 15;8(1):2151. doi: 10.1038/s41467-017-02004-2.
Nat Commun. 2017.
PMID: 29247176
Free PMC article.
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Conserved roles for the dynein intermediate chain and Ndel1 in assembly and activation of dynein.
Okada K, Iyer BR, Lammers LG, Gutierrez PA, Li W, Markus SM, McKenney RJ.
Okada K, et al. Among authors: lammers lg.
Nat Commun. 2023 Sep 20;14(1):5833. doi: 10.1038/s41467-023-41466-5.
Nat Commun. 2023.
PMID: 37730751
Free PMC article.
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Conserved Roles for the Dynein Intermediate Chain and Ndel1 in Assembly and Activation of Dynein.
Okada K, Iyer BR, Lammers LG, Gutierrez P, Li W, Markus SM, McKenney RJ.
Okada K, et al. Among authors: lammers lg.
bioRxiv [Preprint]. 2023 Jan 14:2023.01.13.523097. doi: 10.1101/2023.01.13.523097.
bioRxiv. 2023.
PMID: 36711700
Free PMC article.
Updated.
Preprint.
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