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Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice.
Dufies O, Doye A, Courjon J, Torre C, Michel G, Loubatier C, Jacquel A, Chaintreuil P, Majoor A, Guinamard RR, Gallerand A, Saavedra PHV, Verhoeyen E, Rey A, Marchetti S, Ruimy R, Czerucka D, Lamkanfi M, Py BF, Munro P, Visvikis O, Boyer L. Dufies O, et al. Among authors: lamkanfi m. Nat Microbiol. 2021 Mar;6(3):401-412. doi: 10.1038/s41564-020-00832-5. Epub 2021 Jan 11. Nat Microbiol. 2021. PMID: 33432150 Free PMC article.
Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis.
Vande Walle L, Van Opdenbosch N, Jacques P, Fossoul A, Verheugen E, Vogel P, Beyaert R, Elewaut D, Kanneganti TD, van Loo G, Lamkanfi M. Vande Walle L, et al. Among authors: lamkanfi m. Nature. 2014 Aug 7;512(7512):69-73. doi: 10.1038/nature13322. Epub 2014 Jun 29. Nature. 2014. PMID: 25043000 Free PMC article.
Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia.
Diabate M, Munro P, Garcia E, Jacquel A, Michel G, Obba S, Goncalves D, Luci C, Marchetti S, Demon D, Degos C, Bechah Y, Mege JL, Lamkanfi M, Auberger P, Gorvel JP, Stuart LM, Landraud L, Lemichez E, Boyer L. Diabate M, et al. Among authors: lamkanfi m. PLoS Pathog. 2015 Mar 17;11(3):e1004732. doi: 10.1371/journal.ppat.1004732. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25781937 Free PMC article.
Protective and detrimental roles of inflammasomes in disease.
Saavedra PH, Demon D, Van Gorp H, Lamkanfi M. Saavedra PH, et al. Among authors: lamkanfi m. Semin Immunopathol. 2015 Jul;37(4):313-22. doi: 10.1007/s00281-015-0485-5. Epub 2015 Apr 21. Semin Immunopathol. 2015. PMID: 25895577 Review.
The NEK-sus of the NLRP3 inflammasome.
Van Hauwermeiren F, Lamkanfi M. Van Hauwermeiren F, et al. Among authors: lamkanfi m. Nat Immunol. 2016 Mar;17(3):223-4. doi: 10.1038/ni.3391. Nat Immunol. 2016. PMID: 26882252 No abstract available.
General Strategies in Inflammasome Biology.
Dubois H, Wullaert A, Lamkanfi M. Dubois H, et al. Among authors: lamkanfi m. Curr Top Microbiol Immunol. 2016;397:1-22. doi: 10.1007/978-3-319-41171-2_1. Curr Top Microbiol Immunol. 2016. PMID: 27460802 Review.
Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation.
Van Gorp H, Saavedra PH, de Vasconcelos NM, Van Opdenbosch N, Vande Walle L, Matusiak M, Prencipe G, Insalaco A, Van Hauwermeiren F, Demon D, Bogaert DJ, Dullaers M, De Baere E, Hochepied T, Dehoorne J, Vermaelen KY, Haerynck F, De Benedetti F, Lamkanfi M. Van Gorp H, et al. Among authors: lamkanfi m. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14384-14389. doi: 10.1073/pnas.1613156113. Epub 2016 Nov 22. Proc Natl Acad Sci U S A. 2016. PMID: 27911804 Free PMC article.
Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections.
Hassane M, Demon D, Soulard D, Fontaine J, Keller LE, Patin EC, Porte R, Prinz I, Ryffel B, Kadioglu A, Veening JW, Sirard JC, Faveeuw C, Lamkanfi M, Trottein F, Paget C. Hassane M, et al. Among authors: lamkanfi m. Mucosal Immunol. 2017 Jul;10(4):1056-1068. doi: 10.1038/mi.2016.113. Epub 2017 Jan 4. Mucosal Immunol. 2017. PMID: 28051086 Free article.
Immunology: Gut sensor halts viral attack.
Saavedra PHV, Lamkanfi M. Saavedra PHV, et al. Among authors: lamkanfi m. Nature. 2017 Jun 29;546(7660):606-608. doi: 10.1038/nature23090. Epub 2017 Jun 21. Nature. 2017. PMID: 28636602 No abstract available.
155 results