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Combined MEK and STAT3 Inhibition Uncovers Stromal Plasticity by Enriching for Cancer-Associated Fibroblasts With Mesenchymal Stem Cell-Like Features to Overcome Immunotherapy Resistance in Pancreatic Cancer.
Datta J, Dai X, Bianchi A, De Castro Silva I, Mehra S, Garrido VT, Lamichhane P, Singh SP, Zhou Z, Dosch AR, Messaggio F, Ban Y, Umland O, Hosein PJ, Nagathihalli NS, Merchant NB. Datta J, et al. Among authors: lamichhane p. Gastroenterology. 2022 Dec;163(6):1593-1612. doi: 10.1053/j.gastro.2022.07.076. Epub 2022 Aug 7. Gastroenterology. 2022. PMID: 35948109 Free PMC article.
Tobacco Carcinogen-Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer.
Srinivasan S, Totiger T, Shi C, Castellanos J, Lamichhane P, Dosch AR, Messaggio F, Kashikar N, Honnenahally K, Ban Y, Merchant NB, VanSaun M, Nagathihalli NS. Srinivasan S, et al. Among authors: lamichhane p. Cancer Res. 2018 Nov 1;78(21):6146-6158. doi: 10.1158/0008-5472.CAN-18-0579. Epub 2018 Sep 19. Cancer Res. 2018. PMID: 30232221 Free PMC article.
Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer.
Totiger TM, Srinivasan S, Jala VR, Lamichhane P, Dosch AR, Gaidarski AA 3rd, Joshi C, Rangappa S, Castellanos J, Vemula PK, Chen X, Kwon D, Kashikar N, VanSaun M, Merchant NB, Nagathihalli NS. Totiger TM, et al. Among authors: lamichhane p. Mol Cancer Ther. 2019 Feb;18(2):301-311. doi: 10.1158/1535-7163.MCT-18-0464. Epub 2018 Nov 7. Mol Cancer Ther. 2019. PMID: 30404927 Free PMC article.
Remodeling of Stromal Immune Microenvironment by Urolithin A Improves Survival with Immune Checkpoint Blockade in Pancreatic Cancer.
Mehra S, Garrido VT, Dosch AR, Lamichhane P, Srinivasan S, Singh SP, Zhou Z, De Castro Silva I, Joshi C, Ban Y, Datta J, Gilboa E, Merchant NB, Nagathihalli NS. Mehra S, et al. Among authors: lamichhane p. Cancer Res Commun. 2023 Jul 12;3(7):1224-1236. doi: 10.1158/2767-9764.CRC-22-0329. eCollection 2023 Jul. Cancer Res Commun. 2023. PMID: 37448553 Free PMC article.
Resistance to Checkpoint Inhibition in Cancer Immunotherapy.
Barrueto L, Caminero F, Cash L, Makris C, Lamichhane P, Deshmukh RR. Barrueto L, et al. Among authors: lamichhane p. Transl Oncol. 2020 Mar;13(3):100738. doi: 10.1016/j.tranon.2019.12.010. Epub 2020 Feb 27. Transl Oncol. 2020. PMID: 32114384 Free PMC article. Review.
IL10 Release upon PD-1 Blockade Sustains Immunosuppression in Ovarian Cancer.
Lamichhane P, Karyampudi L, Shreeder B, Krempski J, Bahr D, Daum J, Kalli KR, Goode EL, Block MS, Cannon MJ, Knutson KL. Lamichhane P, et al. Cancer Res. 2017 Dec 1;77(23):6667-6678. doi: 10.1158/0008-5472.CAN-17-0740. Epub 2017 Oct 9. Cancer Res. 2017. PMID: 28993412 Free PMC article.
Novel Delivery Systems for Checkpoint Inhibitors.
Lamichhane P, Deshmukh R, Brown JA, Jakubski S, Parajuli P, Nolan T, Raja D, Badawy M, Yoon T, Zmiyiwsky M, Lamichhane N. Lamichhane P, et al. Among authors: lamichhane n. Medicines (Basel). 2019 Jul 11;6(3):74. doi: 10.3390/medicines6030074. Medicines (Basel). 2019. PMID: 31373327 Free PMC article. Review.
218 results