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IL-6 Trans-signaling Controls Liver Regeneration After Partial Hepatectomy.
Hepatology. 2019 Dec;70(6):2075-2091. doi: 10.1002/hep.30774. Epub 2019 Jul 8.
Hepatology. 2019.
PMID: 31100194
The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling.
Baran P, Hansen S, Waetzig GH, Akbarzadeh M, Lamertz L, Huber HJ, Ahmadian MR, Moll JM, Scheller J.
Baran P, et al. Among authors: lamertz l.
J Biol Chem. 2018 May 4;293(18):6762-6775. doi: 10.1074/jbc.RA117.001163. Epub 2018 Mar 20.
J Biol Chem. 2018.
PMID: 29559558
Free PMC article.
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Soluble gp130 prevents interleukin-6 and interleukin-11 cluster signaling but not intracellular autocrine responses.
Lamertz L, Rummel F, Polz R, Baran P, Hansen S, Waetzig GH, Moll JM, Floss DM, Scheller J.
Lamertz L, et al.
Sci Signal. 2018 Oct 2;11(550):eaar7388. doi: 10.1126/scisignal.aar7388.
Sci Signal. 2018.
PMID: 30279168
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Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases.
Floss DM, Klöcker T, Schröder J, Lamertz L, Mrotzek S, Strobl B, Hermanns H, Scheller J.
Floss DM, et al. Among authors: lamertz l.
Mol Biol Cell. 2016 Jul 15;27(14):2301-16. doi: 10.1091/mbc.E14-12-1645. Epub 2016 May 18.
Mol Biol Cell. 2016.
PMID: 27193299
Free PMC article.
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Transcytosis of IL-11 and Apical Redirection of gp130 Is Mediated by IL-11α Receptor.
Monhasery N, Moll J, Cuman C, Franke M, Lamertz L, Nitz R, Görg B, Häussinger D, Lokau J, Floss DM, Piekorz R, Dimitriadis E, Garbers C, Scheller J.
Monhasery N, et al. Among authors: lamertz l.
Cell Rep. 2016 Jul 26;16(4):1067-1081. doi: 10.1016/j.celrep.2016.06.062. Epub 2016 Jul 14.
Cell Rep. 2016.
PMID: 27425614
Free article.
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Combined deletion of the fibronectin-type III domains and the stalk region results in ligand-independent, constitutive activation of the Interleukin 6 signal-transducing receptor gp130.
Lamertz L, Floss DM, Scheller J.
Lamertz L, et al.
Cytokine. 2018 Oct;110:428-434. doi: 10.1016/j.cyto.2018.05.011. Epub 2018 May 19.
Cytokine. 2018.
PMID: 29789201
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Split2 Protein-Ligation Generates Active IL-6-Type Hyper-Cytokines from Inactive Precursors.
Moll JM, Wehmöller M, Frank NC, Homey L, Baran P, Garbers C, Lamertz L, Axelrod JH, Galun E, Mootz HD, Scheller J.
Moll JM, et al. Among authors: lamertz l.
ACS Synth Biol. 2017 Dec 15;6(12):2260-2272. doi: 10.1021/acssynbio.7b00208. Epub 2017 Nov 29.
ACS Synth Biol. 2017.
PMID: 29136368
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