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Macrolide Inspired Macrocycles as Modulators of the IL-17A/IL-17RA Interaction.
Koštrun S, Fajdetić A, Pešić D, Brajša K, Bencetić Mihaljević V, Jelić D, Petrinić Grba A, Elenkov I, Rupčić R, Kapić S, Ozimec Landek I, Butković K, Grgičević A, Žiher D, Čikoš A, Padovan J, Saxty G, Dack K, Bladh H, Skak-Nielsen T, Feldbaek Nielsen S, Lambert M, Stahlhut M. Koštrun S, et al. Among authors: lambert m. J Med Chem. 2021 Jun 24;64(12):8354-8383. doi: 10.1021/acs.jmedchem.1c00327. Epub 2021 Jun 8. J Med Chem. 2021. PMID: 34100601
Discovery and Early Clinical Development of Isobutyl 1-[8-Methoxy-5-(1-oxo-3H-isobenzofuran-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxylate (LEO 39652), a Novel "Dual-Soft" PDE4 Inhibitor for Topical Treatment of Atopic Dermatitis.
Larsen J, Lambert M, Pettersson H, Vifian T, Larsen M, Ollerstam A, Hegardt P, Eskilsson C, Laursen S, Soehoel A, Skak-Nielsen T, Hansen LM, Knudsen NØ, Eirefelt S, Sørensen MD, Stilou TG, Nielsen SF. Larsen J, et al. Among authors: lambert m. J Med Chem. 2020 Dec 10;63(23):14502-14521. doi: 10.1021/acs.jmedchem.0c00797. Epub 2020 Oct 15. J Med Chem. 2020. PMID: 33054196
Characterizing Cutaneous Drug Delivery Using Open-Flow Microperfusion and Mass Spectrometry Imaging.
Handler AM, Eirefelt S, Lambert M, Johansson F, Hollesen Schefe L, Østergaard Knudsen N, Bodenlenz M, Birngruber T, Sinner F, Huss Eriksson A, Pommergaard Pedersen G, Janfelt C, Troensegaard Nielsen K. Handler AM, et al. Among authors: lambert m. Mol Pharm. 2021 Aug 2;18(8):3063-3072. doi: 10.1021/acs.molpharmaceut.1c00285. Epub 2021 Jul 11. Mol Pharm. 2021. PMID: 34247482
2,681 results