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Computational drug treatment simulations on projections of dysregulated protein networks derived from the myelodysplastic mutanome match clinical response in patients.
Drusbosky L, Medina C, Martuscello R, Hawkins KE, Chang M, Lamba JK, Vali S, Kumar A, Singh NK, Abbasi T, Sekeres MA, Mallo M, Sole F, Bejar R, Cogle CR. Drusbosky L, et al. Among authors: lamba jk. Leuk Res. 2017 Jan;52:1-7. doi: 10.1016/j.leukres.2016.11.004. Epub 2016 Nov 6. Leuk Res. 2017. PMID: 27855285 Free article.
A genomics-informed computational biology platform prospectively predicts treatment responses in AML and MDS patients.
Drusbosky LM, Singh NK, Hawkins KE, Salan C, Turcotte M, Wise EA, Meacham A, Vijay V, Anderson GG, Kim CC, Radhakrishnan S, Ullal Y, Talawdekar A, Sikora H, Nair P, Khanna-Gupta A, Abbasi T, Vali S, Guha S, Farhadfar N, Murthy HS, Horn BN, Leather HL, Castillo P, Tucker C, Cline C, Pettiford L, Lamba JK, Moreb JS, Brown RA, Norkin M, Hiemenz JW, Hsu JW, Slayton WB, Wingard JR, Cogle CR. Drusbosky LM, et al. Among authors: lamba jk. Blood Adv. 2019 Jun 25;3(12):1837-1847. doi: 10.1182/bloodadvances.2018028316. Blood Adv. 2019. PMID: 31208955 Free PMC article. Clinical Trial.
Global Proteomic Profiling of Pediatric AML: A Pilot Study.
Nguyen NHK, Wu H, Tan H, Peng J, Rubnitz JE, Cao X, Pounds S, Lamba JK. Nguyen NHK, et al. Among authors: lamba jk. Cancers (Basel). 2021 Jun 24;13(13):3161. doi: 10.3390/cancers13133161. Cancers (Basel). 2021. PMID: 34202615 Free PMC article.
Polygenic Ara-C Response Score Identifies Pediatric Patients With Acute Myeloid Leukemia in Need of Chemotherapy Augmentation.
Elsayed AH, Cao X, Mitra AK, Wu H, Raimondi S, Cogle C, Al-Mansour Z, Ribeiro RC, Gamis A, Kolb EA, Aplenc R, Alonzo TA, Meshinchi S, Rubnitz J, Pounds S, Lamba JK. Elsayed AH, et al. Among authors: lamba jk. J Clin Oncol. 2022 Mar 1;40(7):772-783. doi: 10.1200/JCO.21.01422. Epub 2022 Jan 6. J Clin Oncol. 2022. PMID: 34990262 Free PMC article.
123 results